SCHEMBL19834697

SCHEMBL19834697

COc1ccccc1C(=O)c1ccccc1I

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.51
CNR2 P34972 1/20 0.50
HSD17B10 Q99714 2/20 0.49
LMNA P02545 2/20 0.49
ALOX15 P16050 1/20 0.49
TSHR P16473 2/20 0.49
GAA P10253 1/20 0.49
MAPT P10636 1/20 0.49
MAPK1 P28482 1/20 0.49
STAT3 P40763 1/20 0.49
STS P08842 1/20 0.48
NPC1 O15118 2/20 0.47
ABCG2 Q9UNQ0 1/20 0.47
RAB9A P51151 1/20 0.47
HTT P42858 2/20 0.47
ELANE P08246 1/20 0.47
CHRM2 P08172 1/20 0.47
CHRM4 P08173 1/20 0.47
CHRM5 P08912 1/20 0.47
CHRM1 P11229 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29658169 0.88 CTSD (0.62) CTSDCNR2HSD17B10LMNAALOX15
SCHEMBL322168 0.88 CTSD (0.62) CTSDCNR2HSD17B10LMNAALOX15
SCHEMBL27789892 0.86 CTSD (0.60) CTSDCNR2HSD17B10LMNAALOX15
SCHEMBL1298701 0.82 MEN1 (0.54) ALOX15TSHRGAAMAPT
SCHEMBL2949130 0.80 KMT2A (0.72) HSD17B10LMNATSHRGAAMAPT
SCHEMBL30758630 0.80 KMT2A (0.72) HSD17B10LMNATSHRGAAMAPT
SCHEMBL3839465 0.80 KMT2A (0.52) HSD17B10ALOX15TSHRGAAMAPT
SCHEMBL20832514 0.79 LMNA (0.56) CTSDCNR2HSD17B10LMNAALOX15
SCHEMBL20520212 0.79 HSD17B10 (0.58) CTSDCNR2HSD17B10LMNAALOX15
SCHEMBL4060271 0.79 LMNA (0.62) CTSDCNR2HSD17B10LMNAALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10747112-B2 Compound, resin, and purification method thereof, material for forming underlayer film for lithography, composition for forming underlayer film, and underlayer film, as well as resist pattern forming method and circuit pattern forming method MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-08-18 US disclosed
EP-3279179-B1 COMPOUND, RESIN, AND PURIFICATION METHOD THEREOF, MATERIAL FOR FORMING UNDERLAYER FILM FOR LITHOGRAPHY, COMPOSITION FOR FORMING UNDERLAYER FILM , AND UNDERLAYER FILM, AS WELL AS RESIST PATTERN FORMING METHOD AND CIRCUIT PATTERN FORMING METHOD. MITSUBISHI GAS CHEMICAL CO (JP) 2019-12-18 EP disclosed
US-20180095368-A1 COMPOUND, RESIN, AND PURIFICATION METHOD THEREOF, MATERIAL FOR FORMING UNDERLAYER FILM FOR LITHOGRAPHY, COMPOSITION FOR FORMING UNDERLAYER FILM, AND UNDERLAYER FILM, AS WELL AS RESIST PATTERN FORMING METHOD AND CIRCUIT PATTERN FORMING METHOD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-04-05 US disclosed
EP-3279179-A1 COMPOUND, RESIN, AND METHOD FOR PURIFYING SAME, UNDERLAYER FILM FORMATION MATERIAL FOR LITHOGRAPHY, UNDERLAYER FILM FORMING COMPOSITION, AND UNDERLAYER FILM, AND METHOD FOR FORMING RESIST PATTERN AND METHOD FOR FORMING CIRCUIT PATTERN Mitsubishi Gas Chemical Company, Inc. (JP) 2018-02-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180095368-A1 COMPOUND, RESIN, AND PURIFICATION METHOD THEREOF, MATERIAL FOR FORMING UNDERLAYER FILM FOR LITHOGRAPHY, COMPOSITION FOR FORMING UNDERLAYER FILM, AND UNDERLAYER FILM, AS WELL AS RESIST PATTERN FORMING METHOD AND CIRCUIT PATTERN FORMING METHOD C5, PRMT9, C9 CTSD 4818/4885CNR2 2798/4885HSD17B10 3888/4885
US-10747112-B2 Compound, resin, and purification method thereof, material for forming underlayer film for lithography, composition for forming underlayer film, and underlayer film, as well as resist pattern forming method and circuit pattern forming method C5, PRMT9, C9 CTSD 4818/4885CNR2 2798/4885HSD17B10 3888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.