Phenethylamine

Phenethylamine

SCHEMBL19837239

NCCc1ccccc1.Nc1ccc(N)cc1

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.84
CYP2A6 P11509 1/20 0.84
SMN1; SMN2 Q16637 1/20 0.84
TAAR1 Q96RJ0 1/20 0.84
LOXL2 Q9Y4K0 1/20 0.84
MAOB P27338 6/20 0.76
MAOA P21397 5/20 0.76
GFER P55789 1/20 0.57
NPC1 O15118 1/20 0.57
RAB9A P51151 1/20 0.57
CYP1A2 P05177 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C19 P33261 1/20 0.54
CYP19A1 P11511 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenethylamine SCHEMBL1331271 0.92
Phenethylamine SCHEMBL1330939 0.92
Phenethylamine SCHEMBL1332244 0.92
Phenethylamine SCHEMBL1799333 0.92 HTR2A (1.00) HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2
Phenethylamine SCHEMBL968 0.92
Phenethylamine SCHEMBL8384113 0.89 HTR2A (0.94) HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2
Phenethylamine SCHEMBL245154 0.89 HTR2A (0.94) HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2
Phenethylamine SCHEMBL20568335 0.89 HTR2A (0.94) HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2
Phenethylamine SCHEMBL10592571 0.89 HTR2A (0.94) HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2
Phenethylamine SCHEMBL837569 0.89 HTR2A (0.94) HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10287235-B2 Isomerization method for 1,3,3-trimethyl-1-(aminomethyl)aminocyclohexane MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2019-05-14 US disclosed
US-20180037537-A1 ISOMERIZATION METHOD FOR 1,3,3-TRIMETHYL-1-(AMINOMETHYL)AMINOCYCLOHEXANE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2018-02-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180037537-A1 ISOMERIZATION METHOD FOR 1,3,3-TRIMETHYL-1-(AMINOMETHYL)AMINOCYCLOHEXANE AP1M1, PRMT1, AP3M1 HTR2A 2401/4885CYP2A6 1691/4885SMN1; SMN2 2661/4885
US-10287235-B2 Isomerization method for 1,3,3-trimethyl-1-(aminomethyl)aminocyclohexane AP1M1, PRMT1, AP3M1 HTR2A 2401/4885CYP2A6 1691/4885SMN1; SMN2 2661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.