Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.94 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.94 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.94 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.94 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.94 |
| ▸ | MAOA | P21397 | 3/20 | 0.64 |
| ▸ | MAOB | P27338 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HTR6 | P50406 | 2/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenethylamine SCHEMBL28974687 | 0.97 | HTR2A (0.89) | HTR2ALOXL2TAAR1CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL23093677 | 0.97 | HTR2A (0.89) | HTR2ALOXL2TAAR1CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL27634208 | 0.97 | HTR2A (1.00) | HTR2ALOXL2TAAR1CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL1330939 | 0.97 | — | — | |
| Phenethylamine SCHEMBL1331271 | 0.97 | — | — | |
| Phenethylamine SCHEMBL1799333 | 0.97 | HTR2A (1.00) | HTR2ALOXL2TAAR1CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL1332244 | 0.97 | — | — | |
| Phenethylamine SCHEMBL968 | 0.97 | — | — | |
| Phenethylamine SCHEMBL8384113 | 0.94 | HTR2A (0.94) | HTR2ALOXL2TAAR1CYP2A6SMN1; SMN2 | |
| Phenethylamine SCHEMBL20568335 | 0.94 | HTR2A (0.94) | HTR2ALOXL2TAAR1CYP2A6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106512992-A | Synthesis method of polyaniline supported palladium with reduced metal content | 扬州大学 | 2017-03-22 | — | — | CN | disclosed |
| US-20160122450-A1 | SYNTHESIS OF A SUBSTITUTED FURAN | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-05-05 | — | — | US | disclosed |
| EP-1904415-B1 | HYDROPHOBING MINERALS AND FILLER MATERIALS | DOW CORNING (US) | 2014-03-12 | — | — | EP | disclosed |
| US-8142856-B2 | Preparing hydrolyzate containing polysiloxanes by hydrolyzing hydrolysable silane or hydrolysable silane mixture in presence of acid hydrolysis catalyst andcombining polysiloxane hydrolyzate with mineral and/or filler and optionally with water and/or a catalyst for condensation of the hydrolyzate | DOW CORNING CORPORATION (US) | 2012-03-27 | — | — | US | disclosed |
| CN-101426477-A | Nanoparticulate carvedilol formulations | ELAN PHARMA INT LTD (IE) | 2009-05-06 | — | — | CN | disclosed |
| US-20080286474-A1 | Hydrophobing Minerals and Filler Materials | DOW SILICONES CORPORATION | 2008-11-20 | — | — | US | disclosed |
| EP-1904415-A2 | HYDROPHOBING MINERALS AND FILLER MATERIALS | Dow Corning Corporation (US) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007009935-A2 | HYDROPHOBING MINERALS AND FILLER MATERIALS | DOW CORNING CORPORATION (US) | 2007-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160122450-A1 | SYNTHESIS OF A SUBSTITUTED FURAN | DCXR, PFAS, FUT6 | HTR2A 2806/4885LOXL2 4274/4885TAAR1 3296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.