Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.52 |
| ▸ | ARG2 | P78540 | 4/20 | 0.47 |
| ▸ | ARG1 | P05089 | 3/20 | 0.47 |
| ▸ | NOS2 | P35228 | 6/20 | 0.46 |
| ▸ | NOS1 | P29475 | 5/20 | 0.46 |
| ▸ | NOS3 | P29474 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | BHMT | Q93088 | 1/20 | 0.43 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2684333 | 0.86 | GSR (0.67) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL128663 | 0.86 | GSR (0.67) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL197363 | 0.86 | GSR (0.67) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL198716 | 0.86 | PMP22 (0.56) | GSRCYP1A2BLMKMT2AALOX15 | |
| SCHEMBL4408300 | 0.86 | PMP22 (0.56) | GSRCYP1A2BLMKMT2AALOX15 | |
| SCHEMBL1512920 | 0.86 | PMP22 (0.56) | GSRCYP1A2BLMKMT2AALOX15 | |
| SCHEMBL27458499 | 0.84 | GSR (0.59) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL5967486 | 0.84 | GSR (0.64) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL31370204 | 0.84 | GSR (0.64) | GSRARG2ARG1NOS2NOS1 | |
| Hydrochloric Acid SCHEMBL21837618 | 0.84 | GSR (0.64) | GSRARG2ARG1NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120009637-A1 | Nitrilases, Nucleic Acids Encoding Them and Methods For Making and Using Them | VERENIUM CORPORATION (US) | 2012-01-12 | — | — | US | disclosed |
| US-8088613-B2 | Nitrilases, nucleic acids encoding them and methods for making and using them | VERENIUM CORPORATION (US) | 2012-01-03 | — | — | US | disclosed |
| US-20110263839-A1 | Nucleic Acids Encoding Nitrilases | VERENIUM CORPORATION (US) | 2011-10-27 | — | — | US | disclosed |
| US-7993901-B2 | Nitrilases and methods for making and using them | VERENIUM CORPORATION (US) | 2011-08-09 | — | — | US | disclosed |
| EP-2327767-A1 | Nitrilases | Verenium Corporation (US) | 2011-06-01 | — | — | EP | disclosed |
| EP-2327766-A1 | Nitrilases | Verenium Corporation (US) | 2011-06-01 | — | — | EP | disclosed |
| EP-2327765-A1 | Nitrilases | Verenium Corporation (US) | 2011-06-01 | — | — | EP | disclosed |
| EP-2319919-A1 | Nitrilases | Verenium Corporation (US) | 2011-05-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263839-A1 | Nucleic Acids Encoding Nitrilases | RNGTT, NSUN2, DNTT | GSR 1856/4885ARG2 1230/4885ARG1 1506/4885 |
| US-20120009637-A1 | Nitrilases, Nucleic Acids Encoding Them and Methods For Making and Using Them | RNGTT, NSUN2, NSUN3 | GSR 1496/4885ARG2 1244/4885ARG1 1532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.