Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PMP22 | Q01453 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | BHMT | Q93088 | 2/20 | 0.53 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.52 |
| ▸ | GSR | P00390 | 2/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL198716 | 1.00 | PMP22 (0.56) | PMP22ALOX15BLMKMT2ABHMT | |
| SCHEMBL1512920 | 1.00 | PMP22 (0.56) | PMP22ALOX15BLMKMT2ABHMT | |
| SCHEMBL198373 | 0.86 | GSR (0.52) | PMP22ALOX15BLMKMT2ABHMT | |
| SCHEMBL25660446 | 0.86 | GSR (0.56) | PMP22ALOX15BLMKMT2ASLC1A3 | |
| SCHEMBL27458499 | 0.84 | GSR (0.59) | PMP22ALOX15BLMKMT2AGSR | |
| SCHEMBL8068164 | 0.84 | GSR (0.68) | PMP22ALOX15BLMKMT2ABHMT | |
| SCHEMBL602426 | 0.84 | GSR (0.68) | PMP22ALOX15BLMKMT2ABHMT | |
| SCHEMBL59989 | 0.82 | BHMT (0.55) | PMP22ALOX15BLMKMT2ABHMT | |
| SCHEMBL1895927 | 0.82 | BHMT (0.55) | PMP22ALOX15BLMKMT2ABHMT | |
| SCHEMBL17039475 | 0.82 | BHMT (0.55) | PMP22ALOX15BLMKMT2ABHMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2036918-A1 | PEPTIDE DERIVATIVE | Vexon, Inc. (JP) | 2009-03-18 | — | — | EP | claimed |
| US-20080009448-A1 | Peptide Derivative | VEXON, INC. (50%) (JP) | 2008-01-10 | — | — | US | claimed |
| EP-2036918-A1 | PEPTIDE DERIVATIVE | Vexon, Inc. (JP) | 2009-03-18 | — | — | EP | disclosed |
| US-20080009448-A1 | Peptide Derivative | VEXON, INC. (50%) (JP) | 2008-01-10 | — | — | US | disclosed |
| WO-1999033864-A1 | PEPTIDE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009448-A1 | Peptide Derivative | ARGLU1, NGLY1, NPR3 | PMP22 3119/4885ALOX15 974/4885BLM 4444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.