Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 7/20 | 0.36 |
| ▸ | DRD4 | P21917 | 7/20 | 0.36 |
| ▸ | DRD3 | P35462 | 7/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 5/20 | 0.31 |
| ▸ | NPC1 | O15118 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19840760 | 0.83 | NOTUM (0.42) | IGF1RALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL19841076 | 0.82 | RAB9A (0.38) | HPGDKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL19840884 | 0.82 | HDAC8 (0.47) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL19840964 | 0.81 | LMNA (0.38) | IGF1RHPGDALDH1A1RAB9ANPC1 | |
| SCHEMBL19841015 | 0.80 | KDM4E (0.39) | HPGDKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL19841082 | 0.80 | NPC1 (0.42) | CA12CA9HPGDKDM4EALDH1A1 | |
| SCHEMBL19840938 | 0.79 | KDM4E (0.35) | HPGDKDM4EALDH1A1HSD17B10RAB9A | |
| SCHEMBL19841066 | 0.79 | CYP2C19 (0.47) | CA12CA9IGF1RALDH1A1LMNA | |
| SCHEMBL19840900 | 0.78 | DPP4 (0.42) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL19840940 | 0.78 | KDM4E (0.34) | HPGDKDM4EALDH1A1HSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884832-B2 | Inhibitors targeting drug-resistant influenza A | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2018-02-06 | — | — | US | disclosed |