Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26997899 | 0.90 | PTPN1 (0.47) | PTPN1KDM4ECYP2C9CYP2C19POLB | |
| SCHEMBL24373554 | 0.86 | PTPN1 (0.52) | PTPN1KDM4ECYP2C9CYP2C19POLB | |
| SCHEMBL4145613 | 0.86 | PTPN1 (0.55) | PTPN1KDM4ECYP2C9CYP2C19POLB | |
| SCHEMBL19116660 | 0.81 | TDP1 (0.59) | PTPN1KDM4ECYP2C9CYP2C19POLB | |
| SCHEMBL16643863 | 0.81 | PTPN1 (0.54) | PTPN1KDM4ECYP2C9CYP2C19POLB | |
| SCHEMBL22657559 | 0.80 | PTPN1 (0.56) | PTPN1KDM4ECYP2C9CYP2C19POLB | |
| SCHEMBL26213401 | 0.79 | PTPN1 (0.49) | PTPN1KDM4ECYP2C9CYP2C19POLB | |
| SCHEMBL12197944 | 0.78 | ALDH1A1 (0.60) | PTPN1KDM4ECYP2C9CYP2C19POLB | |
| SCHEMBL12932588 | 0.78 | POLB (0.53) | PTPN1KDM4ECYP2C9CYP2C19POLB | |
| SCHEMBL12764370 | 0.77 | MEN1 (0.49) | PTPN1KDM4ECYP2C9CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| US-9884127-B2 | Drug-conjugates, conjugation methods, and uses thereof | CONCORTIS BIOSYSTEMS, CORP. (US) | 2018-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | CGAS, GLS2, GLS | PTPN1 3454/4885KDM4E 4338/4885CYP2C9 2594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.