Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18873100 | 0.87 | THRB (0.41) | THRBTSHRALDH1A1CYP3A4HTT | |
| SCHEMBL19757188 | 0.85 | HTT (0.40) | THRBTSHRALDH1A1CYP3A4HTT | |
| SCHEMBL13289971 | 0.84 | TSHR (0.63) | THRBTSHRALDH1A1CYP3A4HTT | |
| SCHEMBL12172633 | 0.84 | TSHR (0.63) | THRBTSHRALDH1A1CYP3A4HTT | |
| SCHEMBL723159 | 0.84 | TSHR (0.63) | THRBTSHRALDH1A1CYP3A4HTT | |
| SCHEMBL14907526 | 0.84 | TSHR (0.63) | THRBTSHRALDH1A1CYP3A4HTT | |
| SCHEMBL19771140 | 0.83 | THRB (0.46) | THRBTSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL19757187 | 0.82 | THRB (0.51) | THRBTSHRALDH1A1CYP3A4HTT | |
| SCHEMBL12172632 | 0.82 | THRB (0.63) | THRBTSHRALDH1A1CYP3A4HTT | |
| SCHEMBL19844190 | 0.82 | HTT (0.34) | THRBTSHRALDH1A1CYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180037817-A1 | POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY | DIC CORPORATION (JP) | 2018-02-08 | — | — | US | disclosed |