Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19844183 | 0.87 | THRB (0.48) | THRBPTPN11ALDH1A1TSHRCYP3A4 | |
| SCHEMBL19771140 | 0.84 | THRB (0.46) | THRBPTPN11ALDH1A1TSHRCYP3A4 | |
| SCHEMBL19757188 | 0.84 | HTT (0.40) | THRBPTPN11ALDH1A1TSHRCYP3A4 | |
| SCHEMBL18873099 | 0.81 | THRB (0.39) | THRBPTPN11ALDH1A1TSHRCYP3A4 | |
| SCHEMBL18200278 | 0.81 | MAPT (0.44) | THRBPTPN11TSHRCYP3A4NPC1 | |
| SCHEMBL19771135 | 0.81 | THRB (0.46) | THRBPTPN11ALDH1A1TSHRHPGD | |
| SCHEMBL19497942 | 0.81 | ALDH1A1 (0.40) | THRBPTPN11ALDH1A1CYP3A4NPC1 | |
| SCHEMBL19497864 | 0.80 | MAPT (0.45) | THRBPTPN11TSHRCYP3A4NPC1 | |
| SCHEMBL19757187 | 0.80 | THRB (0.51) | THRBALDH1A1TSHRCYP3A4HTT | |
| SCHEMBL8728225 | 0.79 | MAOB (0.49) | THRBALDH1A1TSHRCYP3A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017079867-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY | DIC CORPORATION (JP) | 2017-05-18 | — | — | WO | disclosed |