Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.34 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 2/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
| ▸ | USP8 | P40818 | 1/20 | 0.30 |
| ▸ | USP7 | Q93009 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19837398 | 0.79 | MBOAT4 (0.40) | MBOAT4CTSSCTSKXDHHRH4 | |
| SCHEMBL19851263 | 0.79 | MBOAT4 (0.46) | MBOAT4CTSSCTSKXDHHRH4 | |
| SCHEMBL19837353 | 0.79 | MBOAT4 (0.40) | MBOAT4CTSSCTSKXDHHRH4 | |
| SCHEMBL19837356 | 0.79 | MBOAT4 (0.38) | MBOAT4CTSSCTSKPGK1 | |
| Hydrochloric Acid SCHEMBL19837354 | 0.78 | MBOAT4 (0.40) | MBOAT4CTSSCTSKXDHHRH4 | |
| SCHEMBL20500522 | 0.77 | USP8 (0.46) | P2RX3USP8USP7 | |
| SCHEMBL30866463 | 0.77 | USP8 (0.46) | P2RX3USP8USP7 | |
| SCHEMBL26231767 | 0.76 | MBOAT4 (0.41) | MBOAT4P2RX3USP8USP7 | |
| SCHEMBL2302384 | 0.76 | SLC1A5 (0.38) | SLC1A5PGK1KMO | |
| SCHEMBL31361182 | 0.76 | SLC1A5 (0.38) | SLC1A5PGK1KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9994591-B2 | Oxadiazolopyridine derivates for use as ghrelin O-acyl transferase (GOAT) inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-06-12 | — | — | US | disclosed |
| US-20180037594-A1 | Oxadiazolopyridine Derivates for Use as Ghrelin O-Acyl Transferase (GOAT) Inhibitors | BOEHRINGER INGELHEIM INERNATIONAL GMBH (DE) | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037594-A1 | Oxadiazolopyridine Derivates for Use as Ghrelin O-Acyl Transferase (GOAT) Inhibitors | MBOAT4, GIPR, ACAT1 | MBOAT4 1/4885CTSS 4341/4885CTSK 3945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.