Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 15/20 | 0.54 |
| ▸ | NPC1 | O15118 | 14/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | AXL | P30530 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19837773 | 0.88 | CSF1R (0.49) | RAB9ANPC1SMN1; SMN2CSF1RRET | |
| SCHEMBL18054780 | 0.81 | CHRNB2 (0.47) | RAB9ANPC1HPGDSMN1; SMN2CSF1R | |
| SCHEMBL18039593 | 0.80 | BRAF (0.50) | RAB9ANPC1SMN1; SMN2CSF1RRET | |
| SCHEMBL18039522 | 0.79 | ALDH1A1 (0.49) | RAB9ANPC1SMN1; SMN2CSF1RRET | |
| SCHEMBL18039606 | 0.77 | CSF1R (0.52) | RAB9ANPC1SMN1; SMN2CSF1RRET | |
| SCHEMBL18054772 | 0.75 | MEN1 (0.49) | RAB9ANPC1PKMHPGDSMN1; SMN2 | |
| SCHEMBL18054771 | 0.74 | CSF1R (0.49) | SMN1; SMN2CSF1RRETPDGFRBFLT3 | |
| SCHEMBL18054783 | 0.74 | CSF1R (0.49) | RAB9ANPC1HPGDNFKB1NFKB2 | |
| SCHEMBL18039713 | 0.74 | CSF1R (0.49) | RAB9ANPC1PKMSMN1; SMN2NAMPT | |
| SCHEMBL18039692 | 0.73 | LMNA (0.53) | HPGDCSF1RRETPDGFRBFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180037589-A1 | THIENODIAZEPINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS (KR) | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037589-A1 | THIENODIAZEPINE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT | RET, PDGFRB, FLT3 | RAB9A 783/4885NPC1 3396/4885PKM 1429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.