Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16540439 | 0.88 | MAPT (0.45) | MAPTKDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL16540787 | 0.87 | MAPT (0.49) | MAPTKDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL16541002 | 0.87 | MAPT (0.59) | MAPTKDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL16540970 | 0.87 | ALDH1A1 (0.50) | MAPTKDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL16540713 | 0.84 | KDM4E (0.54) | MAPTKDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL18012115 | 0.81 | MAPT (0.43) | MAPTKDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL18012109 | 0.80 | MAPT (0.58) | MAPTKDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL17997083 | 0.79 | MAPT (0.54) | MAPTKDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL18012131 | 0.79 | MAPT (0.49) | MAPTKDM4ESMN1; SMN2RAB9ANPC1 | |
| SCHEMBL16540678 | 0.78 | MAPK1 (0.54) | MAPTKDM4ESMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890132-B2 | Process for the preparation of anti-inflammatory aroylbenzofuran compounds | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-02-13 | — | — | US | disclosed |