Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16540787 | 0.92 | MAPT (0.49) | MAPTKDM4EMCL1MAOBSMN1; SMN2 | |
| SCHEMBL18012115 | 0.89 | MAPT (0.43) | MAPTKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL18012133 | 0.88 | MAPT (0.50) | MAPTKDM4EMCL1MAOBSMN1; SMN2 | |
| SCHEMBL16541114 | 0.88 | MAPT (0.50) | MAPTKDM4EMCL1MAOBSMN1; SMN2 | |
| SCHEMBL16540439 | 0.82 | MAPT (0.45) | MAPTKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL16540811 | 0.81 | MAPT (0.46) | MAPTKDM4EMCL1SMN1; SMN2NPC1 | |
| SCHEMBL18012132 | 0.79 | KDM4E (0.47) | MAPTKDM4EMCL1SMN1; SMN2NPC1 | |
| SCHEMBL16540660 | 0.79 | KDM4E (0.47) | MAPTKDM4EMCL1SMN1; SMN2NPC1 | |
| SCHEMBL19847107 | 0.79 | MAPT (0.60) | MAPTKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL16540970 | 0.78 | ALDH1A1 (0.50) | MAPTKDM4ESMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160229827-A1 | A PROCESS FOR THE PREPARATION OF ANTI-INFLAMMATORY AROYLBENZOFURAN COMPOUNDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229827-A1 | A PROCESS FOR THE PREPARATION OF ANTI-INFLAMMATORY AROYLBENZOFURAN COMPOUNDS | LITAF, IL1B, CYP2F1 | MAPT 4537/4885KDM4E 2789/4885MCL1 2167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.