Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 13/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17997083 | 0.92 | MAPT (0.54) | ALDH1A1MAPTNPC1KMT2ATP53 | |
| SCHEMBL16540678 | 0.91 | MAPK1 (0.54) | ALDH1A1TSHRMAPTNPC1KMT2A | |
| SCHEMBL16541002 | 0.91 | MAPT (0.59) | ALDH1A1MAPTNPC1KMT2ATP53 | |
| SCHEMBL16540439 | 0.88 | MAPT (0.45) | ALDH1A1TSHRMAPTNPC1KMT2A | |
| SCHEMBL19847107 | 0.87 | MAPT (0.60) | ALDH1A1TSHRMAPTNPC1KMT2A | |
| SCHEMBL16540787 | 0.87 | MAPT (0.49) | ALDH1A1TSHRMAPTNPC1KMT2A | |
| SCHEMBL16547881 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TSHRMAPTNPC1KMT2A | |
| SCHEMBL16541079 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TSHRMAPTNPC1KMT2A | |
| SCHEMBL18012109 | 0.83 | MAPT (0.58) | ALDH1A1MAPTNPC1KMT2ATP53 | |
| SCHEMBL16540729 | 0.80 | PTPN1 (0.48) | ALDH1A1TSHRMAPTNPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890132-B2 | Process for the preparation of anti-inflammatory aroylbenzofuran compounds | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-02-13 | — | — | US | claimed |
| US-20160229827-A1 | A PROCESS FOR THE PREPARATION OF ANTI-INFLAMMATORY AROYLBENZOFURAN COMPOUNDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-08-11 | — | — | US | claimed |
| WO-2015029062-A1 | A PROCESS FOR THE PREPARATION OF ANTI-INFLAMMATORY AROYLBENZOFURAN COMPOUNDS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RSEARCH (IN) | 2015-03-05 | — | — | WO | claimed |
| US-9890132-B2 | Process for the preparation of anti-inflammatory aroylbenzofuran compounds | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-02-13 | — | — | US | disclosed |
| US-9890132-B2 | Process for the preparation of anti-inflammatory aroylbenzofuran compounds | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-02-13 | — | — | US | disclosed |
| US-9890132-B2 | Process for the preparation of anti-inflammatory aroylbenzofuran compounds | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-02-13 | — | — | US | disclosed |
| US-20160229827-A1 | A PROCESS FOR THE PREPARATION OF ANTI-INFLAMMATORY AROYLBENZOFURAN COMPOUNDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-08-11 | — | — | US | disclosed |
| US-20160229827-A1 | A PROCESS FOR THE PREPARATION OF ANTI-INFLAMMATORY AROYLBENZOFURAN COMPOUNDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-08-11 | — | — | US | disclosed |
| US-20160229827-A1 | A PROCESS FOR THE PREPARATION OF ANTI-INFLAMMATORY AROYLBENZOFURAN COMPOUNDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-08-11 | — | — | US | disclosed |
| WO-2015029062-A1 | A PROCESS FOR THE PREPARATION OF ANTI-INFLAMMATORY AROYLBENZOFURAN COMPOUNDS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RSEARCH (IN) | 2015-03-05 | — | — | WO | disclosed |
| WO-2015029062-A1 | A PROCESS FOR THE PREPARATION OF ANTI-INFLAMMATORY AROYLBENZOFURAN COMPOUNDS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RSEARCH (IN) | 2015-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229827-A1 | A PROCESS FOR THE PREPARATION OF ANTI-INFLAMMATORY AROYLBENZOFURAN COMPOUNDS | LITAF, IL1B, CYP2F1 | ALDH1A1 253/4885TSHR 3947/4885MAPT 4537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.