Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.61 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19833935 | 0.91 | MGLL (0.73) | MGLLNR3C2ALDH1A1MAPTNR3C1 | |
| SCHEMBL19847833 | 0.80 | MGLL (0.51) | MGLLNR3C2 | |
| SCHEMBL19833774 | 0.76 | MGLL (0.56) | MGLLNR3C2 | |
| SCHEMBL19834081 | 0.76 | MGLL (1.00) | MGLLNR3C2NR3C1PGR | |
| SCHEMBL19833719 | 0.75 | MGLL (0.84) | MGLLNR3C2NR3C1PGR | |
| SCHEMBL19833992 | 0.74 | MGLL (0.57) | MGLLNR3C2 | |
| SCHEMBL19833805 | 0.74 | MGLL (0.57) | MGLLNR3C2 | |
| SCHEMBL22386265 | 0.73 | MGLL (0.70) | MGLLNR3C2 | |
| SCHEMBL21723014 | 0.73 | MGLL (0.47) | MGLLALDH1A1 | |
| SCHEMBL19847847 | 0.72 | MGLL (0.62) | MGLLNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3279191-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2020-09-02 | — | — | EP | disclosed |
| EP-3279191-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-02-07 | — | — | EP | disclosed |