Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19848056 | 0.93 | NR3C2 (0.44) | MGLLNR3C2NR3C1 | |
| SCHEMBL19833904 | 0.91 | MGLL (0.57) | MGLLALDH1A1POLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL19833872 | 0.86 | MGLL (0.51) | MGLLNR3C2NR3C1 | |
| SCHEMBL19834174 | 0.83 | MGLL (0.49) | MGLLNR3C2NR3C1 | |
| SCHEMBL19847847 | 0.80 | MGLL (0.62) | MGLLTP53NR3C2 | |
| SCHEMBL22386265 | 0.79 | MGLL (0.70) | MGLLNR3C2 | |
| SCHEMBL19847923 | 0.78 | MGLL (0.66) | MGLLL3MBTL1NR3C2 | |
| SCHEMBL19833864 | 0.78 | NR3C2 (0.45) | MGLLMAPTNR3C2NR3C1 | |
| SCHEMBL19834105 | 0.78 | MGLL (0.43) | MGLLMAPTNR3C2NR3C1 | |
| SCHEMBL19848105 | 0.78 | MAP3K5 (0.37) | POLBTP53LMNAMAPTNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3279191-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2020-09-02 | — | — | EP | disclosed |
| EP-3279191-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-02-07 | — | — | EP | disclosed |