SCHEMBL198501

SCHEMBL198501

C1CCC(N[SiH](NC2CCCCC2)NC2CCCCC2)CC1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
HSD17B10 Q99714 1/20 0.50
EPHX1 P07099 5/20 0.39
CYP3A4 P08684 2/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CA1 P00915 2/20 0.39
ADH1B P00325 2/20 0.39
ADH1C P00326 2/20 0.39
ADH1A P07327 2/20 0.39
CA12 O43570 2/20 0.39
CA7 P43166 2/20 0.39
CA14 Q9ULX7 2/20 0.39
KDM4E B2RXH2 2/20 0.39
ADH4 P08319 1/20 0.39
TP53 P04637 1/20 0.39
MAPT P10636 1/20 0.39
EPHX2 P34913 1/20 0.39
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27336230 0.97 ALDH1A1 (0.44) ALDH1A1HSD17B10EPHX1CYP3A4NPC1
SCHEMBL27412858 0.75 ALDH1A1 (0.45) ALDH1A1HSD17B10EPHX1CYP3A4NPC1
SCHEMBL21327703 0.75 ALDH1A1 (0.45) ALDH1A1HSD17B10EPHX1CYP3A4NPC1
SCHEMBL17612823 0.75 ALDH1A1 (0.45) ALDH1A1HSD17B10EPHX1CYP3A4NPC1
SCHEMBL10882892 0.75 ALDH1A1 (0.45) ALDH1A1HSD17B10EPHX1CYP3A4NPC1
SCHEMBL8207166 0.75 ALDH1A1 (0.45) ALDH1A1HSD17B10EPHX1CYP3A4NPC1
SCHEMBL25249653 0.71 ALDH1A1 (0.41) ALDH1A1HSD17B10EPHX1CYP3A4NPC1
SCHEMBL9452392 0.71 ALDH1A1 (0.41) ALDH1A1HSD17B10EPHX1CYP3A4NPC1
SCHEMBL10883501 0.71 ALDH1A1 (0.40) ALDH1A1HSD17B10EPHX1CYP3A4NPC1
SCHEMBL10652990 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8202928-B2 Amine-cured silicone compositions resistant to hydrocarbon fluid and uses thereof CONTINENTAL AUTOMOTIVE SYSTEMS, INC (US) 2012-06-19 US claimed
EP-1242540-B1 USE OF FLUID RESISTANT SILICONE COMPOSITIONS FOR SEALING MAGNESIUM ALLOY COMPONENTS HENKEL CORP (US) 2007-04-04 EP claimed
JP-2003535152-A 2003-11-25 JP claimed
EP-1242540-A1 FLUID RESISTANT SILICONE COMPOSITIONS FOR SEALING MAGNESIUM ALLOY COMPONENTS LOCTITE CORPORATION (US) 2002-09-25 EP claimed
US-6444740-B1 SILICONES; ADHESIVES, SEALS LOCTITE CORPORATION 2002-09-03 US claimed
WO-2001036537-A1 FLUID RESISTANT SILICONE COMPOSITIONS FOR SEALING MAGNESIUM ALLOY COMPONENTS LOCTITE CORPORATION (US) 2001-05-25 WO claimed
WO-2000027910-A1 OIL RESISTANT COMPOSITIONS LOCTITE CORPORATION (US) 2000-05-18 WO claimed
WO-1999065979-A1 FUEL RESISTANT SILICONES LOCTITE CORPORATION (US) 1999-12-23 WO claimed
WO-1999066012-A2 OIL RESISTANT SILICONES LOCTITE CORPORATION (US) 1999-12-23 WO claimed
US-10711135-B2 High temperature resistant, two component, low viscosity silicone composition Henkel IP & Holding GmbH and Henkel AG & Co. KGaA (DE) 2020-07-14 US disclosed
CN-111387832-A Cooking utensil with thermochromic coating 卢世荣 2020-07-10 CN disclosed
CN-111265117-A Cooking utensil with thermochromic coating and manufacturing method thereof 卢世荣 2020-06-12 CN disclosed
EP-2456824-B1 CURABLE SILICONE COMPOSITIONS CONTAINING REACTIVE NON-SILOXANE-CONTAINING RESINS Henkel IP & Holding GmbH (DE) 2018-09-05 EP disclosed
EP-3320046-A1 HIGH TEMPERATURE RESISTANT, TWO COMPONENT, LOW VISCOSITY SILICONE COMPOSITION Henkel AG & Co. KGaA (DE) 2018-05-16 EP disclosed
EP-0098911-B1 IMPROVED PROCESS FOR THE PREPARATION OF OXIMATOHYDRIDOSILANES AND AMINOXYHYDRIDOSILANES UNION CARBIDE CORPORATION (US) 1986-04-16 EP disclosed
US-4491669-A Mixed alkoxyaminosilanes, methods of making same and vulcanizing silicons prepared therefrom PETRARCH SYSTEMS INC. (US) 1985-01-01 US disclosed
US-4395564-A REACTING AN ALCOHOL WITH SILYL-AMINE UNION CARBIDE CORPORATION (US) 1983-07-26 US disclosed
US-4384131-A Process for the preparation of oximatohydridosilanes and aminoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1983-05-17 US disclosed
US-4208316-A REINFORCING FILLER HARDENABLE ELASTOMERS DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1980-06-17 US disclosed
US-4170700-A AMINO-SILICON COMPOUND, CARBON DIOXIDE SWS SILICONES CORPORATION (US) 1979-10-09 US disclosed