Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207166 | 1.00 | ALDH1A1 (0.45) | ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4 | |
| SCHEMBL10652990 | 0.97 | — | — | |
| SCHEMBL10882892 | 0.82 | ALDH1A1 (0.45) | ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4 | |
| SCHEMBL21327703 | 0.82 | ALDH1A1 (0.45) | ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4 | |
| SCHEMBL10883501 | 0.79 | ALDH1A1 (0.40) | ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4 | |
| SCHEMBL25249653 | 0.78 | ALDH1A1 (0.41) | ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4 | |
| SCHEMBL9452392 | 0.78 | ALDH1A1 (0.41) | ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4 | |
| SCHEMBL198501 | 0.75 | ALDH1A1 (0.50) | ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4 | |
| SCHEMBL20816152 | 0.72 | ALDH1A1 (0.36) | ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4 | |
| SCHEMBL27336230 | 0.71 | ALDH1A1 (0.44) | ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1112383-C | Olefin polymers prepared with substituted indenyl containing metal complexes | DOW CHEMICAL CO (US) | 2003-06-25 | — | — | CN | disclosed |
| CN-1098857-C | Substituted indenyl contg. metal complexes and olefin polymerization process | DOW CHEMICAL CO (US) | 2003-01-15 | — | — | CN | disclosed |
| CN-1258303-A | Olefin polymers prepared with substituted indenyl containing metal complexes | DOW CHEMICAL CO (US) | 2000-06-28 | — | — | CN | disclosed |