SCHEMBL8207166

SCHEMBL8207166

C[SiH](C)NC1CCCCC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
HSD17B10 Q99714 1/20 0.45
SIGMAR1 Q99720 2/20 0.37
EPHX1 P07099 6/20 0.36
CYP3A4 P08684 2/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
CA1 P00915 2/20 0.36
CA12 O43570 2/20 0.36
CA7 P43166 2/20 0.36
CA14 Q9ULX7 2/20 0.36
KDM4E B2RXH2 2/20 0.36
ADH1B P00325 1/20 0.36
ADH1C P00326 1/20 0.36
ADH1A P07327 1/20 0.36
ADH4 P08319 1/20 0.36
TP53 P04637 1/20 0.36
MAPT P10636 1/20 0.36
EPHX2 P34913 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27412858 1.00 ALDH1A1 (0.45) ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4
SCHEMBL10652990 0.97
SCHEMBL10882892 0.82 ALDH1A1 (0.45) ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4
SCHEMBL21327703 0.82 ALDH1A1 (0.45) ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4
SCHEMBL10883501 0.79 ALDH1A1 (0.40) ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4
SCHEMBL25249653 0.78 ALDH1A1 (0.41) ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4
SCHEMBL9452392 0.78 ALDH1A1 (0.41) ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4
SCHEMBL198501 0.75 ALDH1A1 (0.50) ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4
SCHEMBL20816152 0.72 ALDH1A1 (0.36) ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4
SCHEMBL27336230 0.71 ALDH1A1 (0.44) ALDH1A1HSD17B10SIGMAR1EPHX1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108026637-A Method for depositing conformal metal or metalloid silicon nitride films and resulting films 弗萨姆材料美国有限责任公司 2018-05-11 CN claimed
CN-104962877-A Compositions and methods for depositing silicon oxide films AIR PROD & CHEM 2015-10-07 CN claimed
EP-2718304-B1 METHOD OF PREPARING ETHYLENE- -OLEFIN-DIENE COPOLYMER SK INNOVATION CO LTD (KR) 2016-03-09 EP disclosed
US-6136995-A Process for producing aminosilane compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-24 US disclosed
US-5032660-A Polysiloxanes, titanium-phosphate organic curing agent TIOXIDE GROUP PLC (GB) 1991-07-16 US disclosed
EP-0273456-A2 Vapor phase alcoholysis of aminosilanes and carbamatosilanes UNION CARBIDE CORPORATION (US) 1988-07-06 EP disclosed
US-4730074-A Vapor phase alcoholysis of aminosilanes and carbamatosilanes UNION CARBIDE CORPORATION (US) 1988-03-08 US disclosed
EP-0098911-B1 IMPROVED PROCESS FOR THE PREPARATION OF OXIMATOHYDRIDOSILANES AND AMINOXYHYDRIDOSILANES UNION CARBIDE CORPORATION (US) 1986-04-16 EP disclosed
EP-0098911-A1 Improved process for the preparation of oximatohydridosilanes and aminoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1984-01-25 EP disclosed
EP-0098912-A1 Process for the preparation of alkoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1984-01-25 EP disclosed
US-4395564-A REACTING AN ALCOHOL WITH SILYL-AMINE UNION CARBIDE CORPORATION (US) 1983-07-26 US disclosed
US-4384131-A Process for the preparation of oximatohydridosilanes and aminoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1983-05-17 US disclosed