Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | GAA | P10253 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3958329 | 1.00 | MAPT (0.59) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL14003573 | 0.88 | RAD52 (0.52) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL16089612 | 0.87 | TDO2 (0.49) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL16089616 | 0.81 | RAB9A (0.56) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9390146 | 0.81 | PTGS1 (0.51) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL16657388 | 0.81 | LMNA (0.60) | GAAMEN1KMT2ALMNAPTGS1 | |
| SCHEMBL16657411 | 0.81 | GAA (0.58) | MAPTKDM4EGAALMNAPTGS1 | |
| SCHEMBL17058278 | 0.81 | PTGS1 (0.43) | MAPTALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL4714454 | 0.80 | PTGS1 (0.59) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL4720695 | 0.80 | MAPT (0.45) | MAPTALDH1A1KDM4EGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018023851-A1 | IMIDAZOPYRIDINE THIOGLYCOLIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 山东大学 | 2018-02-08 | — | — | WO | disclosed |