Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19851079 | 0.86 | PDE4B (0.54) | PDE4BPDE4DPOLBALDH1A1TSHR | |
| SCHEMBL16084474 | 0.74 | PDE4B (0.52) | PDE4BPDE4DPOLBALDH1A1TSHR | |
| SCHEMBL5778683 | 0.70 | PDE4B (0.54) | PDE4BPDE4DPOLBALDH1A1TSHR | |
| SCHEMBL5775573 | 0.70 | PDE4B (0.54) | PDE4BPDE4DPOLBALDH1A1TSHR | |
| SCHEMBL5775620 | 0.70 | PDE4B (0.54) | PDE4BPDE4DPOLBALDH1A1TSHR | |
| SCHEMBL22612126 | 0.68 | CYP11B2 (0.51) | TP53 | |
| SCHEMBL23678973 | 0.68 | PDE4B (0.52) | PDE4BPDE4DPOLBALDH1A1TSHR | |
| SCHEMBL1104426 | 0.67 | TP53 (0.58) | TP53 | |
| SCHEMBL927345 | 0.66 | PDE4B (0.50) | PDE4BPDE4DPOLBALDH1A1TSHR | |
| SCHEMBL928134 | 0.66 | PDE4B (0.47) | PDE4BPDE4DPOLBALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018023851-A1 | IMIDAZOPYRIDINE THIOGLYCOLIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 山东大学 | 2018-02-08 | — | — | WO | disclosed |