Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5775573 | 1.00 | PDE4B (0.54) | PDE4BPDE4DALDH1A1TSHRHSD17B10 | |
| SCHEMBL5775620 | 1.00 | PDE4B (0.54) | PDE4BPDE4DALDH1A1TSHRHSD17B10 | |
| SCHEMBL16084474 | 0.95 | PDE4B (0.52) | PDE4BPDE4DALDH1A1TSHRHSD17B10 | |
| SCHEMBL9688984 | 0.86 | TP53 (0.57) | PDE4BPDE4DALDH1A1TSHRHSD17B10 | |
| SCHEMBL9539176 | 0.85 | TP53 (0.62) | PDE4BPDE4DALDH1A1TSHRHSD17B10 | |
| SCHEMBL19851079 | 0.82 | PDE4B (0.54) | PDE4BPDE4DALDH1A1TSHRHSD17B10 | |
| SCHEMBL21311255 | 0.76 | OPRM1 (0.59) | ALDH1A1HCAR1MAPK1KDM4ETP53 | |
| SCHEMBL14582733 | 0.76 | PDE4B (0.49) | PDE4BPDE4DALDH1A1TSHRHSD17B10 | |
| SCHEMBL2193920 | 0.76 | HCAR1 (0.51) | PDE4BPDE4DALDH1A1TSHRHSD17B10 | |
| SCHEMBL2929873 | 0.74 | RPS6KB1 (0.58) | HCAR1MAPK1TP53MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7098220-B2 | Imidazopyridine derivatives, preparation method and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2006-08-29 | — | — | US | disclosed |
| EP-1558612-B1 | IMIDAZOPYRIDINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2006-08-23 | — | — | EP | disclosed |
| US-20060069117-A1 | Imidazopyridine derivatives, preparation method and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2006-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069117-A1 | Imidazopyridine derivatives, preparation method and pharmaceutical compositions containing same | PRKAA1, PRKAB1, PRKAB2 | PDE4B 1257/4885PDE4D 1425/4885ALDH1A1 1174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.