Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11347877 | 0.74 | GAA (0.50) | GAAKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL4004912 | 0.73 | MAPT (0.48) | GAAKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL29492714 | 0.73 | GAA (0.50) | GAAKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL24270834 | 0.73 | GAA (0.50) | GAAKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL21697451 | 0.73 | EGFR (0.47) | GAAKDM4EMAPTALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL3061295 | 0.70 | NOS2 (0.41) | GAAKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL5084625 | 0.69 | MAPT (0.67) | GAAKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL6567725 | 0.68 | GAA (0.56) | GAAKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL5080900 | 0.67 | MAPT (0.64) | GAAKDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL15081851 | 0.67 | MAPT (0.53) | GAAKDM4EMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018023851-A1 | IMIDAZOPYRIDINE THIOGLYCOLIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 山东大学 | 2018-02-08 | — | — | WO | disclosed |