Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | MC5R | P33032 | 4/20 | 0.51 |
| ▸ | MC4R | P32245 | 3/20 | 0.51 |
| ▸ | MC3R | P41968 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MC1R | Q01726 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4923929 | 0.86 | HDAC8 (0.66) | HDAC8HDAC1HDAC3HDAC2MC5R | |
| SCHEMBL13021557 | 0.84 | MC5R (0.54) | HDAC8HDAC1HDAC3HDAC2MC5R | |
| SCHEMBL6889945 | 0.82 | FFAR1 (0.60) | HDAC8HDAC1HDAC3HDAC2MC5R | |
| SCHEMBL7446128 | 0.81 | MEN1 (0.54) | HDAC8HDAC1HDAC3HDAC2MC5R | |
| SCHEMBL5848162 | 0.80 | L3MBTL1 (0.60) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL4049756 | 0.80 | ALDH1A1 (0.55) | HDAC8HDAC1HDAC3HDAC2MEN1 | |
| SCHEMBL6172461 | 0.78 | HDAC1 (0.57) | HDAC8HDAC1FFAR1CYP1A2 | |
| SCHEMBL6008141 | 0.77 | MC5R (0.71) | HDAC8HDAC1HDAC3HDAC2MC5R | |
| SCHEMBL5556807 | 0.76 | KMT2A (0.57) | HDAC8HDAC1HDAC3HDAC2MC5R | |
| SCHEMBL7311581 | 0.74 | HDAC1 (0.56) | HDAC8HDAC1HDAC3HDAC2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026866-A1 | LIPID-SUBSTITUTED AMINO 1,2-AND 1,3-DIOL COMPOUNDS AS MODULATORS OF TLR2 DIMERIZATION | NEUROPORE THERAPIES, INC. (US) | 2018-02-08 | — | — | WO | disclosed |