Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC5R | P33032 | 5/20 | 0.71 |
| ▸ | MC4R | P32245 | 3/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | MC3R | P41968 | 3/20 | 0.67 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.58 |
| ▸ | MC1R | Q01726 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017226 | 0.94 | MC5R (0.65) | MC5RMC4RMAPK1MC3RROCK1 | |
| Hydrochloric Acid SCHEMBL31120720 | 0.92 | MC5R (0.62) | MC5RMC4RMAPK1MC3RROCK1 | |
| Hydrochloric Acid SCHEMBL31120721 | 0.92 | MC5R (0.62) | MC5RMC4RMAPK1MC3RROCK1 | |
| SCHEMBL5703530 | 0.88 | MC5R (0.64) | MC5RMC4RMAPK1MC3RROCK1 | |
| SCHEMBL5703579 | 0.88 | MC5R (0.59) | MC5RMC4RMAPK1MC3RROCK1 | |
| SCHEMBL7250915 | 0.88 | MC5R (0.69) | MC5RMC4RMAPK1MC3RROCK1 | |
| SCHEMBL27502280 | 0.88 | MC5R (0.59) | MC5RMC4RMAPK1MC3RROCK1 | |
| SCHEMBL8089377 | 0.87 | MC5R (0.62) | MC5RMC4RMAPK1MC3RROCK1 | |
| SCHEMBL31414285 | 0.87 | MC5R (0.62) | MC5RMC4RMAPK1MC3RROCK1 | |
| SCHEMBL7443349 | 0.87 | MC5R (0.62) | MC5RMC4RMAPK1MC3RROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683191-B2 | Organic salts and method for producing chiral organic compounds | Studiangesellschaft Kohle mbH (DE) | 2010-03-23 | — | — | US | disclosed |
| US-7683191-B2 | Organic salts and method for producing chiral organic compounds | Studiangesellschaft Kohle mbH (DE) | 2010-03-23 | — | — | US | disclosed |
| US-20090030216-A1 | ORGANIC SALTS AND METHOD FOR PRODUCING CHIRAL ORGANIC COMPOUNDS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2009-01-29 | — | — | US | disclosed |
| US-20090030216-A1 | ORGANIC SALTS AND METHOD FOR PRODUCING CHIRAL ORGANIC COMPOUNDS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2009-01-29 | — | — | US | disclosed |
| WO-2007098741-A2 | ORGANIC SALTS AND METHOD FOR PRODUCING CHIRAL ORGANIC COMPOUNDS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2007-09-07 | — | — | WO | disclosed |
| EP-1207161-B1 | NOVEL ISOINDOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2006-01-18 | — | — | EP | disclosed |
| US-6777410-B2 | SUCH AS 9-(2-METHOXYPHENYL)-3-(1-METHYLETHYL)-(1,3)OXAZOLO-(2,3)ISOINDOLE-2,5(3H,9H)-DIONE; DIABETES AND COMPLICATIONS; OBESITY | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-08-17 | — | — | US | disclosed |
| US-20040053923-A1 | Novel isoindole derivatives | BANYU PHARMACEUTICAL CO., LTD. | 2004-03-18 | — | — | US | disclosed |
| US-6608098-B1 | Diabetes or obesity, 2-(4-(3-isopropyl-2,5-dioxo-2,3-dihydro-1H-pyrrolo(2,1-a) isoindol-9(5H)-yl)phenoxy)-N-propylacetamide | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2003-08-19 | — | — | US | disclosed |
| EP-1207161-A1 | NOVEL ISOINDOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-05-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030216-A1 | ORGANIC SALTS AND METHOD FOR PRODUCING CHIRAL ORGANIC COMPOUNDS | ICMT, OTC, PNPO | MC5R 1226/4885MC4R 2424/4885MAPK1 4105/4885 |
| US-20040053923-A1 | Novel isoindole derivatives | GPR119, SLC5A2, SLC5A1 | MC5R 62/4885MC4R 32/4885MAPK1 481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.