SCHEMBL1985205

SCHEMBL1985205

S=C=Nc1ccc(C=Cc2ccc(N=C=S)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.54
P2RY6 Q15077 3/20 0.54
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
HSD17B10 Q99714 3/20 0.42
KDM4E B2RXH2 2/20 0.42
USP2 O75604 2/20 0.42
ALDH1A1 P00352 2/20 0.42
LTA P01374 2/20 0.42
CYP3A4 P08684 2/20 0.42
MAPT P10636 2/20 0.42
HPGD P15428 2/20 0.42
P2RX3 P56373 2/20 0.42
RAD51 Q06609 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
RAD1 O60671 1/20 0.42
PNMT P11086 1/20 0.35
TRPA1 O75762 1/20 0.32
RELA Q04206 1/20 0.32
ESR1 P03372 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1985203 1.00 MIF (0.54) MIFP2RY6CA1CA2HSD17B10
SCHEMBL5941069 0.91 MIF (0.64) MIFP2RY6CA1CA2HSD17B10
SCHEMBL5941068 0.91 MIF (0.64) MIFP2RY6CA1CA2HSD17B10
SCHEMBL4200596 0.86 FBP1 (0.43) MIFP2RY6CA1CA2HSD17B10
SCHEMBL4200593 0.86 FBP1 (0.43) MIFP2RY6CA1CA2HSD17B10
SCHEMBL14015554 0.84 RELA (0.44) MIFP2RY6CA1CA2KDM4E
SCHEMBL5157555 0.84 RELA (0.53) HSD17B10KDM4EALDH1A1MAPTTDP1
SCHEMBL5157560 0.84 RELA (0.53) HSD17B10KDM4EALDH1A1MAPTTDP1
Bitoscanate SCHEMBL157128 0.84 MIF (0.72) MIFP2RY6CA1CA2HSD17B10
SCHEMBL4195532 0.82 RELA (0.59) P2RY6KDM4EALDH1A1MAPTRELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3906415-B1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR ENHANCING CD8+ T CELL-DEPENDENT IMMUNE RESPONSES IN SUBJECTS SUFFERING FROM CANCER INST NAT SANTE RECH MED (FR) 2026-04-15 EP disclosed
US-12595517-B2 Method to treat and stratify a patient suffering from a cancer INSERM (INSTITUTE NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2026-04-07 US disclosed
US-20260035471-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR ENHANCING CD8+ T CELL-DEPENDENT IMMUNE RESPONSES IN SUBJECTS SUFFERING FROM CANCER INST NAT SANTE RECH MED (FR) 2026-02-05 US disclosed
EP-4211273-B1 METHOD TO TREAT AND STRATIFICATE A PATIENT SUFFERING FROM A CANCER INST NAT SANTE RECH MED (FR) 2025-10-29 EP disclosed
WO-2025109147-A1 METHOD TO PREDICT THE RISK OF A CARDIOVASCULAR EVENT IN A PATIENT WITH TYPE 2 DIABETES Institut National de la Santé et de la Recherche Médicale (FR) 2025-05-30 WO disclosed
US-12291752-B2 Methods for predicting the survival time and treatment responsiveness of a patient suffering from a solid cancer with a signature of at least 7 genes INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) 2025-05-06 US disclosed
WO-2025078632-A1 METHODS OF PROGNOSIS AND TREATMENT OF PATIENTS SUFFERING FROM CANCER Institut National de la Santé et de la Recherche Médicale (FR) 2025-04-17 WO disclosed
WO-2025073765-A1 METHODS OF PROGNOSIS AND TREATMENT OF PATIENTS SUFFERING FROM MELANOMA Institut National de la Santé et de la Recherche Médicale (FR) 2025-04-10 WO disclosed
WO-2025068340-A1 METHOD TO PREDICT AML OUTCOME Institut National de la Santé et de la Recherche Médicale (FR) 2025-04-03 WO disclosed
WO-2025045894-A1 METHODS AND KITS FOR DIAGNOSING CAUSE OF NEPHROTIC SYNDROME AND GUIDING THERAPY Institut National de la Santé et de la Recherche Médicale (FR) 2025-03-06 WO disclosed
US-20070042386-A1 Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system NANOGEN, INC. 2007-02-22 US disclosed
WO-2006011273-A1 METHOD OF INHIBITING POSTISCHEMIC REPERFUSION-INDUCED CELL DEATH AND CELL DEATH INHIBITOR JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2006-02-02 WO disclosed
US-6911310-B2 Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system NANOGEN, INC. (US) 2005-06-28 US disclosed
US-6906179-B2 Antibody to SNIP1 THE GENERAL HOSPITAL CORPORATION (US) 2005-06-14 US disclosed
EP-1067134-B1 Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to-donor energy transfer system NANOTRONICS INC (US) 2004-07-28 EP disclosed
US-6416953-B1 BIOSENSOR COMPRISING PHOTONIC ENERGY SENSOR, POLYNUCLEOTIDE LINKED TO AT LEAST TWO DONOR CHROMOPHORES, SECOND POLYNUCLEOTIDE LINKED TO ACCEPTOR CHROMOPHORE POSITIONED BY LINKAGE AT DONOR-ACCEPTOR TRANSFER DISTANCE FROM DONOR NANOGEN, INC. 2002-07-09 US disclosed
US-6177259-B1 SCREENING FOR INHIBITORS BY INCUBATING CASPASE, POLYGLUTAMINE PEPTIDE, AND CANDIDATE WHERE REDUCTION IN COMPLEX FORMATION INDICATES INHIBITOR; TREATMENT OF NERVOUS SYSTEM DISORDERS SUCH AS HUNTINGTON'S DISEASE PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2001-01-23 US disclosed
EP-0620822-A4 HYBRIDIZATION OF POLYNUCLEOTIDES CONJUGATED WITH CHROMOPHORES AND FLUOROPHORES TO GENERATE DONOR-TO-DONOR ENERGY TRANSFER SYSTEM. NANOTRONICS INC (US) 1996-01-10 EP disclosed
EP-0620822-A1 HYBRIDIZATION OF POLYNUCLEOTIDES CONJUGATED WITH CHROMOPHORES AND FLUOROPHORES TO GENERATE DONOR-TO-DONOR ENERGY TRANSFER SYSTEM NANOTRONICS, INC. (US) 1994-10-26 EP disclosed
WO-1993009128-A1 HYBRIDIZATION OF POLYNUCLEOTIDES CONJUGATED WITH CHROMOPHORES AND FLUOROPHORES TO GENERATE DONOR-TO-DONOR ENERGY TRANSFER SYSTEM NANOTRONICS, INC. (US) 1993-05-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595517-B2 Method to treat and stratify a patient suffering from a cancer PDCD1, CD274, PDCD4 MIF 1237/4885P2RY6 2809/4885CA1 3206/4885
US-20260035471-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR ENHANCING CD8+ T CELL-DEPENDENT IMMUNE RESPONSES IN SUBJECTS SUFFERING FROM CANCER CD274, PDCD1LG2, PDCD1 MIF 2365/4885P2RY6 2730/4885CA1 2175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.