SCHEMBL5157555

SCHEMBL5157555

CN(C)c1ccc(/C=C/c2ccc(N=C=S)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.53
APP P05067 6/20 0.52
MAPT P10636 5/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
ALDH1A1 P00352 4/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
ALOX15 P16050 2/20 0.50
KDM4E B2RXH2 2/20 0.50
CASP1 P29466 2/20 0.50
HBB P68871 2/20 0.50
THRB P10828 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
TP53 P04637 2/20 0.50
MAPK1 P28482 2/20 0.50
HSD17B10 Q99714 2/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5157560 1.00 RELA (0.53) RELAAPPMAPTMEN1KMT2A
SCHEMBL249847 0.89 ALDH1A1 (0.52) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL1985203 0.84 MIF (0.54) RELAMAPTALDH1A1KDM4EHSD17B10
SCHEMBL1985205 0.84 MIF (0.54) RELAMAPTALDH1A1KDM4EHSD17B10
SCHEMBL2467692 0.83 ALDH1A1 (0.59) MAPTMEN1KMT2AALDH1A1ALOX15
SCHEMBL671704 0.83 ALDH1A1 (0.59) MAPTMEN1KMT2AALDH1A1ALOX15
SCHEMBL11588273 0.79 ALDH1A1 (0.63) RELAAPPMAPTMEN1KMT2A
SCHEMBL27918671 0.79 ALDH1A1 (0.53) MAPTMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL13467434 0.78 RELA (0.81) RELAAPPMAPTMEN1KMT2A
SCHEMBL1714446 0.78 RELA (0.81) RELAAPPMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0984281-B1 A homogeneous assay for determining analyte DADE BEHRING MARBURG GMBH (DE) 2007-01-03 EP disclosed
EP-1418430-A2 A homogeneous assay for determining analyte Dade Behring Marburg GmbH (DE) 2004-05-12 EP disclosed
EP-0984282-B1 Particles having an incorporated composition comprising a chemiluminescent compound DADE BEHRING MARBURG GMBH (DE) 2003-07-30 EP disclosed
EP-0515194-B1 Assay methods utilizing induced luminescence DADE BEHRING MARBURG GMBH (DE) 2001-10-31 EP disclosed
EP-0984281-A2 A homogeneous assay for determining analyte Dade Behring Marburg GmbH (DE) 2000-03-08 EP disclosed
EP-0984282-A2 Particles having an incorporated composition comprising a chemiluminescent compound Dade Behring Marburg GmbH (DE) 2000-03-08 EP disclosed
EP-0653066-B1 PHOTOACTIVATABLE CHEMILUMINESCENT MATRICES BEHRINGWERKE AG (DE) 1998-01-28 EP disclosed
US-5709994-A PHOTOSENSITIZER, SINGLET OXYGEN GENERATION SYNTEX (U.S.A.) INC. (US) 1998-01-20 US disclosed
US-5618732-A COMBINING IN A MEDIUM A CHEMILUMINESCENT CAPABLE OF EMITTING LIGHT UPON IRRIDATION AND A SOLID MATRIX HAVING A PHOTOSENSITIZER WHICH UPON ACTIVATION GENERATES A SINGLET OXYGEN, WHICH ACTIVATES LUMINESCENT, COMPARING DECAY TIME BEHRINGWERKE AG (DE) 1997-04-08 US disclosed
US-5445944-A Reacting with hydrogen donor SYNTEX (U.S.A.) INC. (US) 1995-08-29 US disclosed
US-4328311-A USEFUL IN IMMUNOASSAY SYVA COMPANY (US) 1982-05-04 US disclosed
US-4277437-A CHEMILUMINESCENT SOURCE, QUENCHER MOLECULE SYVA COMPANY (US) 1981-07-07 US disclosed
US-4261968-A QUALITATIVE AND QUANTITATIVE ANALYSES SYVA COMPANY (US) 1981-04-14 US disclosed
US-4235869-A ANTIBODY FRAGMENTS MONOVALENT RECEPTOR SYVA COMPANY (US) 1980-11-25 US disclosed
US-4233402-A CHEMICAL ANALYSIS OF A BINDING PAIR OF LIGANDS AND ENZYMES BY LIGHT SIGNALS SYVA COMPANY (US) 1980-11-11 US disclosed
US-4220450-A Chemically induced fluorescence immunoassay SYVA COMPANY (US) 1980-09-02 US disclosed
US-4220722-A ACYLATION, AMIDATION, SULFIDING SYVA COMPANY (US) 1980-09-02 US disclosed
US-4199559-A DETERMINING THE PRESENCE OR AMOUNT OF A LIGAND OR ANTIBODIES SYVA COMPANY (US) 1980-04-22 US disclosed
US-4174384-A Fluorescence quenching with immunological pairs in immunoassays SYVA COMPANY (US) 1979-11-13 US disclosed
US-3996345-A Fluorescence quenching with immunological pairs in immunoassays SYVA COMPANY (US) 1976-12-07 US disclosed