Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RPA1 | P27694 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1986031 | 0.91 | PDE4D (0.41) | TP53PDE4DMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL1988695 | 0.89 | CNR1 (0.45) | TP53RXFP1CNR1CNR2PDE4D | |
| SCHEMBL1985253 | 0.88 | CNR1 (0.38) | TP53CNR1CNR2PDE4DMAPT | |
| SCHEMBL1985549 | 0.86 | MAPT (0.40) | TP53RXFP1PDE4DMAPTL3MBTL1 | |
| SCHEMBL1987136 | 0.85 | TP53 (0.46) | TP53RXFP1CNR1CNR2PDE4D | |
| SCHEMBL1983924 | 0.85 | MAPT (0.36) | TP53PDE4DMAPTALDH1A1HTT | |
| SCHEMBL1983836 | 0.81 | PDE4D (0.38) | TP53PDE4DMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL1984671 | 0.80 | RXRA (0.39) | TP53PDE4DMAPTALDH1A1HTT | |
| SCHEMBL1987824 | 0.79 | KMT2A (0.40) | TP53CNR1CNR2MAPTALDH1A1 | |
| SCHEMBL1986012 | 0.78 | MAPT (0.42) | TP53PDE4DMAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1602656-B1 | PYRAZOLE DERIVATIVES HAVING AFFINITY FOR CB1 AND/OR CB2 RECEPTORS | NEUROSCIENZE PHARMANESS S C A R L (IT) | 2011-06-29 | — | — | EP | claimed |