Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 1/20 | 0.44 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204083 | 0.84 | KCNE1 (0.38) | KCNE1KCNQ1ABCB1CYP2C9ATM | |
| SCHEMBL7760656 | 0.83 | KCNE1 (0.37) | KCNE1KCNQ1ABCB1CYP2C9ATM | |
| SCHEMBL19839249 | 0.81 | ABCB1 (0.43) | KCNE1KCNQ1ABCB1CYP2C9GAA | |
| SCHEMBL28400315 | 0.80 | HTT (0.40) | KCNE1KCNQ1CYP2C9SMN1; SMN2GAA | |
| SCHEMBL29272200 | 0.77 | NPC1 (0.44) | KCNE1KCNQ1CYP2C9SMN1; SMN2LMNA | |
| SCHEMBL16291560 | 0.74 | CYP3A4 (0.35) | ABCB1CYP2C9ATMGAAPKM | |
| SCHEMBL2818050 | 0.73 | KCNE1 (0.49) | KCNE1KCNQ1ABCB1ATMABCC9 | |
| SCHEMBL7156979 | 0.72 | CRHBP (0.36) | KCNE1KCNQ1ABCB1CYP2C9CRHBP | |
| SCHEMBL5511497 | 0.72 | KCNE1 (0.37) | KCNE1KCNQ1ABCB1CYP2C9ATM | |
| SCHEMBL21408674 | 0.72 | KCNE1 (0.51) | KCNE1KCNQ1ABCB1ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11186564-B2 | Dual NAV1.2/5HT2a inhibitors for treating CNS disorders | SUNOVION PHARMACEUTICALS INC. (US) | 2021-11-30 | — | — | US | disclosed |
| US-20190194163-A1 | DUAL NAV1.2/5HT2a INHIBITORS FOR TREATING CNS DISORDERS | SUNOVION PHARMACEUTICALS INC. (US) | 2019-06-27 | — | — | US | disclosed |
| WO-2018026371-A1 | DUAL NAV1.2/5HT2A INHIBITORS FOR TREATING CNS DISORDERS | SUNOVION PHARMACEUTICALS INC. (US) | 2018-02-08 | — | — | WO | disclosed |
| CN-107001362-A | Heteroaryl compound as BTK inhibitor and application thereof | 默克专利有限公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-1871235-A | Azabicyclic-substituted fused heteroaryl compounds for the treatment of disease | UPJOHN CO (US) | 2006-11-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194163-A1 | DUAL NAV1.2/5HT2a INHIBITORS FOR TREATING CNS DISORDERS | SCN2A, HTR2A, HTR2C | KCNE1 299/4885KCNQ1 101/4885ABCB1 264/4885 |
| US-11186564-B2 | Dual NAV1.2/5HT2a inhibitors for treating CNS disorders | SCN2A, HTR2A, HTR2C | KCNE1 299/4885KCNQ1 101/4885ABCB1 264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.