Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | THRA | P10827 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676691 | 0.90 | TSHR (0.52) | TSHRMAPTTHRATHRBMAPK1 | |
| SCHEMBL17689248 | 0.81 | THRB (0.45) | TSHRMAPTTHRATHRBGLA | |
| SCHEMBL13238290 | 0.81 | ALDH1A1 (0.54) | TSHRMAPTTHRATHRBGLA | |
| SCHEMBL677393 | 0.79 | ALDH1A1 (0.55) | TSHRMAPTTHRATHRBGLA | |
| SCHEMBL5478851 | 0.79 | TSHR (0.58) | TSHRMAPTTHRATHRBMAPK1 | |
| SCHEMBL18771396 | 0.78 | TSHR (0.51) | TSHRMAPTTHRATHRBGLA | |
| SCHEMBL14441425 | 0.78 | MAPT (0.47) | TSHRMAPTGLAHTTKMT2A | |
| SCHEMBL772928 | 0.77 | TSHR (0.61) | TSHRMAPTGLAKMT2AMEN1 | |
| SCHEMBL16352072 | 0.75 | TSHR (0.51) | TSHRMAPTTHRATHRBMAPK1 | |
| SCHEMBL10485988 | 0.74 | MAPT (0.42) | TSHRMAPTGLAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3494157-B1 | STABILIZERS FOR BROMINATED POLYMERIC FLAME RETARDANTS | BROMINE COMPOUNDS LTD (IL) | 2021-03-03 | — | — | EP | disclosed |
| WO-2018025266-A1 | STABILIZERS FOR BROMINATED POLYMERIC FLAME RETARDANTS | BROMINE COMPOUNDS LTD. (IL) | 2018-02-08 | — | — | WO | disclosed |