SCHEMBL676691

SCHEMBL676691

CCC(O)COc1c(Br)cc(Br)cc1Br

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
MAPT P10636 4/20 0.47
THRB P10828 5/20 0.46
THRA P10827 4/20 0.46
MAPK1 P28482 2/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 4/20 0.41
NPSR1 Q6W5P4 1/20 0.41
ALDH1A1 P00352 2/20 0.39
ALOX15 P16050 2/20 0.36
LMNA P02545 1/20 0.36
HSD17B10 Q99714 1/20 0.36
KDM4E B2RXH2 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
MEN1 O00255 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ALOX12 P18054 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19852575 0.90 TSHR (0.45) TSHRMAPTTHRBTHRAMAPK1
SCHEMBL5478851 0.88 TSHR (0.58) TSHRMAPTTHRBTHRAMAPK1
SCHEMBL677393 0.88 ALDH1A1 (0.55) TSHRMAPTTHRBTHRAMAPK1
SCHEMBL17689248 0.87 THRB (0.45) TSHRMAPTTHRBTHRAMAPK1
SCHEMBL16352072 0.84 TSHR (0.51) TSHRMAPTTHRBTHRAMAPK1
SCHEMBL18771396 0.84 TSHR (0.51) TSHRMAPTTHRBTHRAMAPK1
SCHEMBL10711308 0.83 TSHR (0.54) TSHRMAPTTHRBTHRAMAPK1
SCHEMBL12197650 0.83 ALDH1A1 (0.60) TSHRMAPTTHRBTHRAMAPK1
SCHEMBL680993 0.81 TSHR (0.48) TSHRMAPTTHRBTHRAMAPK1
SCHEMBL14525658 0.80 ALDH1A1 (0.43) TSHRMAPTTHRBTHRAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365817-A1 FLAME RETARDANT FORMULATIONS FOR WOOD COATING BROMINE COMPOUNDS LTD. (IL) 2023-11-16 US disclosed
US-20230128079-A1 ANTIMONY FREE FLAME-RETARDED EPOXY COMPOSITIONS BROMINE COMPOUNDS LTD. (IL) 2023-04-27 US disclosed
US-20230128079-A1 ANTIMONY FREE FLAME-RETARDED EPOXY COMPOSITIONS BROMINE COMPOUNDS LTD. (IL) 2023-04-27 US disclosed
US-11560448-B2 Antimony free flame-retarded epoxy compositions BROMINE COMPOUNDS LTD. (IL) 2023-01-24 US disclosed
EP-3555230-B1 ANTIMONY FREE FLAME-RETARDED EPOXY COMPOSITIONS BROMINE COMPOUNDS LTD (IL) 2021-09-22 EP disclosed
US-11111376-B2 Flame-retarded styrene-containing formulations BROMINE COMPOUNDS LTD. (IL) 2021-09-07 US disclosed
EP-3281542-B1 POLYESTER FIBERS FOR ARTIFICIAL HAIR, PROCESS FOR PRODUCING SAME, AND HAIR ORNAMENT PRODUCT INCLUDING SAME KANEKA CORP (JP) 2021-05-05 EP disclosed
EP-3601425-B1 FLAME-RETARDED STYRENE-CONTAINING COMPOSITIONS BROMINE COMPOUNDS LTD (IL) 2021-03-10 EP disclosed
EP-3494157-B1 STABILIZERS FOR BROMINATED POLYMERIC FLAME RETARDANTS BROMINE COMPOUNDS LTD (IL) 2021-03-03 EP disclosed
EP-3601436-B1 FLAME-RETARDED STYRENE-CONTAINING FORMULATIONS BROMINE COMPOUNDS LTD (IL) 2021-01-13 EP disclosed
US-20120309869-A1 FLAME RETARDED COMPOSITIONS BROMINE COMPOUNDS LTD. (IL) 2012-12-06 US disclosed
US-20120309869-A1 FLAME RETARDED COMPOSITIONS BROMINE COMPOUNDS LTD. (IL) 2012-12-06 US disclosed
US-8067497-B2 Flame-retardant for engineering thermoplastic applications BROMINE COMPOUNDS LTD. (IL) 2011-11-29 US disclosed
US-8067497-B2 Flame-retardant for engineering thermoplastic applications BROMINE COMPOUNDS LTD. (IL) 2011-11-29 US disclosed
WO-2011117865-A1 High impact polystyrene flame retarded compositions BROMINE COMPOUNDS LTD. (IL) 2011-09-29 WO disclosed
US-20110160362-A1 FLAME-RETARDED COMPOSITIONS OF STYRENE-CONTAINING POLYMERS BROMINE COMPOUNDS LTD. 2011-06-30 US disclosed
US-20110160362-A1 FLAME-RETARDED COMPOSITIONS OF STYRENE-CONTAINING POLYMERS BROMINE COMPOUNDS LTD. 2011-06-30 US disclosed
US-20100113630-A1 Flame retardant Composition BROMINE COMPOUNDS LTD. (IL) 2010-05-06 US disclosed
US-20100113630-A1 Flame retardant Composition BROMINE COMPOUNDS LTD. (IL) 2010-05-06 US disclosed
WO-2007132463-A1 FLAME RETARDANT COMPOSITION BROMINE COMPOUNDS LTD. (IL) 2007-11-22 WO disclosed