Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16863572 | 1.00 | RCE1 (0.45) | RCE1PPARGPPARALTA4HSIGMAR1 | |
| SCHEMBL16859407 | 1.00 | RCE1 (0.45) | RCE1PPARGPPARALTA4HSIGMAR1 | |
| SCHEMBL19852683 | 1.00 | RCE1 (0.45) | RCE1PPARGPPARALTA4HSIGMAR1 | |
| SCHEMBL16859422 | 1.00 | RCE1 (0.45) | RCE1PPARGPPARALTA4HSIGMAR1 | |
| SCHEMBL19739505 | 1.00 | RCE1 (0.45) | RCE1PPARGPPARALTA4HSIGMAR1 | |
| SCHEMBL17417060 | 0.89 | FFAR1 (0.40) | PPARGPPARALDHAFFAR1L3MBTL1 | |
| SCHEMBL19852656 | 0.89 | FFAR1 (0.40) | PPARGPPARALDHAFFAR1L3MBTL1 | |
| SCHEMBL28610510 | 0.89 | FFAR1 (0.40) | PPARGPPARALDHAFFAR1L3MBTL1 | |
| SCHEMBL17892914 | 0.89 | FFAR1 (0.40) | PPARGPPARALDHAFFAR1L3MBTL1 | |
| SCHEMBL17417013 | 0.85 | LTA4H (0.45) | RCE1PPARGPPARALTA4HSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240408-B1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-04-08 | — | — | EP | disclosed |
| US-20190359557-A1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2019-11-28 | — | — | US | disclosed |
| US-10252989-B2 | Picolinamides with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-04-09 | — | — | US | disclosed |
| US-10173971-B2 | Picolinamides with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-01-08 | — | — | US | disclosed |
| US-20180037541-A1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180037541-A1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | CYP51A1, CYP1A2, FKBP14 | RCE1 313/4885PPARG 2359/4885PPARA 2281/4885 |
| US-20190359557-A1 | PICOLINAMIDES WITH FUNGICIDAL ACTIVITY | CYP51A1, CYP1A2, FKBP14 | RCE1 313/4885PPARG 2359/4885PPARA 2281/4885 |
| US-10173971-B2 | Picolinamides with fungicidal activity | CYP51A1, CYP1A2, FKBP14 | RCE1 313/4885PPARG 2359/4885PPARA 2281/4885 |
| US-10252989-B2 | Picolinamides with fungicidal activity | CYP51A1, CYP1A2, FKBP14 | RCE1 313/4885PPARG 2359/4885PPARA 2281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.