SCHEMBL19852789

SCHEMBL19852789

C[SiH](C)C#Cc1c2cc3c(cc2c(C#C[Si](C)(C)C)c2cc4c(cc12)c1cccc2c5cc6c(C#C[Si](C)(C)C)c7cc8c(cc7c(C#C[Si](C)(C)C)c6cc5c5cccc4c5c12)c1cccc2ccc4cccc8c4c21)c1cccc2ccc4cccc3c4c21

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.35
ALDH1A1 P00352 1/20 0.35
THRB P10828 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
ERBB2 P04626 1/20 0.33
FYN P06241 1/20 0.33
MAOA P21397 1/20 0.33
ACHE P22303 1/20 0.33
AHR P35869 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17856237 0.90 CYP1A2 (0.42) CYP1A2ALDH1A1THRBHPGDHSD17B10
SCHEMBL17856238 0.72 HSP90AA1 (0.40) ALDH1A1HPGDHSD17B10ERBB2FYN
SCHEMBL17856236 0.70 PGR (0.31)
SCHEMBL14514096 0.70 ELANE (0.39) CYP1A2ALDH1A1HPGDHSD17B10
SCHEMBL652147 0.69 ELANE (0.41) CYP1A2ALDH1A1HPGDHSD17B10
SCHEMBL5014197 0.68 CYP1A2 (0.38) CYP1A2ALDH1A1HPGDHSD17B10ERBB2
SCHEMBL6866809 0.68 CYP1A2 (0.44) CYP1A2ALDH1A1THRBHPGDHSD17B10
SCHEMBL656268 0.67 ELANE (0.37) CYP1A2ALDH1A1HPGDHSD17B10ACHE
SCHEMBL4851864 0.67 ALDH1A1 (0.74) CYP1A2ALDH1A1THRBHPGDHSD17B10
SCHEMBL718325 0.67 ALDH1A1 (0.31) CYP1A2ALDH1A1THRBHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10340049-B2 Alpha/beta radiation shielding materials SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (US) 2019-07-02 US disclosed
US-20180040387-A1 Alpha/Beta Radiation Shielding Materials BATTELLE SAVANNAH RIVER ALLIANCE, LLC 2018-02-08 US disclosed