Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.40 |
| ▸ | KDM4A | O75164 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.40 |
| ▸ | TET3 | O43151 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 8/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL1521033 | 1.00 | CYP1A2 (0.43) | CYP1A2CASRTET2KDM4AKDM4C | |
| SCHEMBL198528 | 0.92 | CYP1A2 (0.50) | CYP1A2TET2KDM4AKDM4CKDM2A | |
| SCHEMBL198527 | 0.92 | CYP1A2 (0.50) | CYP1A2TET2KDM4AKDM4CKDM2A | |
| Hydrochloric Acid SCHEMBL1934550 | 0.90 | CYP1A2 (0.48) | CYP1A2TET2KDM4AKDM4CKDM2A | |
| Hydrochloric Acid SCHEMBL2257624 | 0.90 | CYP1A2 (0.48) | CYP1A2TET2KDM4AKDM4CKDM2A | |
| SCHEMBL2984816 | 0.81 | CYP1A2 (0.48) | CYP1A2TET2KDM4AKDM4CKDM2A | |
| SCHEMBL2984814 | 0.81 | CYP1A2 (0.48) | CYP1A2TET2KDM4AKDM4CKDM2A | |
| SCHEMBL15405381 | 0.79 | LMNA (0.42) | CYP1A2FOLH1TSHRLMNAPMP22 | |
| Sulfuric Acid SCHEMBL1521198 | 0.79 | TDP1 (0.37) | CASRFOLH1MAPT | |
| Sulfuric Acid SCHEMBL1521195 | 0.79 | TDP1 (0.37) | CASRFOLH1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102039179-B | Catalytic composition for preparing amide and method for preparing amide | CHINA PETROCHEMICAL DEV CORP | 2013-03-06 | — | — | CN | claimed |
| US-8367865-B2 | Method and catalyst composition for preparing amide | China Petrichemical Development Corporation (TW) | 2013-02-05 | — | — | US | claimed |
| CN-102039179-A | Catalytic composition for preparing amide and method for preparing amide | CHINA PETROCHEMICAL DEV CORP | 2011-05-04 | — | — | CN | claimed |
| EP-2308831-A1 | Method and catalyst composition comprising an amino acid-ionic liquid and a Bronsted acid, for preparing amide | China Petrochemical Development Corporation (TW) | 2011-04-13 | — | — | EP | claimed |
| US-20110077429-A1 | METHOD AND CATALYST COMPOSITION FOR PREPARING AMIDE | CHINA PETROCHEMICAL DEVELOPMENT CORPORATION (TW) | 2011-03-31 | — | — | US | claimed |
| US-8552180-B2 | Method for separating amide from amino acid ionic liquid | CHINA PETROCHEMICAL DEVELOPMENT CORPORATION (TW) | 2013-10-08 | — | — | US | disclosed |
| US-8524895-B2 | Method for preparing amide | CHINA PETROCHEMICAL DEVELOPMENT CORPORATION (TW) | 2013-09-03 | — | — | US | disclosed |
| CN-102039179-B | Catalytic composition for preparing amide and method for preparing amide | CHINA PETROCHEMICAL DEV CORP | 2013-03-06 | — | — | CN | disclosed |
| US-8367865-B2 | Method and catalyst composition for preparing amide | China Petrichemical Development Corporation (TW) | 2013-02-05 | — | — | US | disclosed |
| US-20110105793-A1 | METHOD FOR SEPARATING AMIDE FROM AMINO ACID IONIC LIQUID | CHINA PETROCHEMICAL DEVELOPMENT CORPORATION (TW) | 2011-05-05 | — | — | US | disclosed |
| CN-102039179-A | Catalytic composition for preparing amide and method for preparing amide | CHINA PETROCHEMICAL DEV CORP | 2011-05-04 | — | — | CN | disclosed |
| EP-2308831-A1 | Method and catalyst composition comprising an amino acid-ionic liquid and a Bronsted acid, for preparing amide | China Petrochemical Development Corporation (TW) | 2011-04-13 | — | — | EP | disclosed |
| US-20110077429-A1 | METHOD AND CATALYST COMPOSITION FOR PREPARING AMIDE | CHINA PETROCHEMICAL DEVELOPMENT CORPORATION (TW) | 2011-03-31 | — | — | US | disclosed |
| US-20100063274-A1 | METHOD FOR PREPARING AMIDE | CHINA PETROCHEMICAL DEVELOPMENT CORPORATION, Taipei(Taiwan) (TW) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105793-A1 | METHOD FOR SEPARATING AMIDE FROM AMINO ACID IONIC LIQUID | ASNS, AADAT, SLC1A5 | CYP1A2 4306/4885CASR 2571/4885TET2 4450/4885 |
| US-20100063274-A1 | METHOD FOR PREPARING AMIDE | ASNS, KMO, AADAT | CYP1A2 483/4885CASR 2954/4885TET2 1143/4885 |
| US-20110077429-A1 | METHOD AND CATALYST COMPOSITION FOR PREPARING AMIDE | BCAT2, BCAT1, KYAT3 | CYP1A2 858/4885CASR 4716/4885TET2 1517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.