Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL215049 | 1.00 | L3MBTL1 (0.39) | L3MBTL1NOS2NOS3NOS1MBTD1 | |
| SCHEMBL27420810 | 1.00 | L3MBTL1 (0.39) | L3MBTL1NOS2NOS3NOS1MBTD1 | |
| SCHEMBL16563030 | 1.00 | L3MBTL1 (0.39) | L3MBTL1NOS2NOS3NOS1MBTD1 | |
| SCHEMBL9595528 | 1.00 | L3MBTL1 (0.39) | L3MBTL1NOS2NOS3NOS1MBTD1 | |
| SCHEMBL19211543 | 1.00 | L3MBTL1 (0.39) | L3MBTL1NOS2NOS3NOS1MBTD1 | |
| SCHEMBL12926132 | 1.00 | L3MBTL1 (0.39) | L3MBTL1NOS2NOS3NOS1MBTD1 | |
| SCHEMBL16763803 | 1.00 | L3MBTL1 (0.39) | L3MBTL1NOS2NOS3NOS1MBTD1 | |
| SCHEMBL661111 | 1.00 | L3MBTL1 (0.39) | L3MBTL1NOS2NOS3NOS1MBTD1 | |
| SCHEMBL474365 | 0.93 | — | — | |
| SCHEMBL27420798 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11904307-B2 | Organometallic complexes of sequential tetradentate monoanionic ligands and uses thereof in ring opening polymerization of cyclic esters | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2024-02-20 | — | — | US | disclosed |
| EP-3414275-B1 | ORGANOMETALLIC COMPLEXES OF SEQUENTIAL TETRADENTATE MONOANIONIC LIGANDS AND USES THEREOF IN RING OPENING POLYMERIZATION OF CYCLIC ESTERS | UNIV RAMOT (IL) | 2023-07-05 | — | — | EP | disclosed |
| US-20220395820-A1 | ORGANOMETALLIC COMPLEXES OF SEQUENTIAL TETRADENTATE MONOANIONIC LIGANDS AND USES THEREOF IN RING OPENING POLYMERIZATION OF CYCLIC ESTERS | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2022-12-15 | — | — | US | disclosed |
| US-11452998-B2 | Organometallic complexes of sequential tetradentate monoanionic ligands and uses thereof in ring opening polymerization of cyclic esters | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2022-09-27 | — | — | US | disclosed |
| EP-3494108-B1 | SYNTHESIS OF (S)-2-AMINO-4-METHYL-1-((R)-2-METHYLOXIRANE-2-YL)-PENTAN-1-ONE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | AMGEN INC (US) | 2020-10-28 | — | — | EP | disclosed |
| US-20190039058-A1 | ORGANOMETALLIC COMPLEXES OF SEQUENTIAL TETRADENTATE MONOANIONIC LIGANDS AND USES THEREOF IN RING OPENING POLYMERIZATION OF CYCLIC ESTERS | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2019-02-07 | — | — | US | disclosed |
| WO-2018027021-A1 | SYNTHESIS OF (S)-2-AMINO-4-METHYL-1-((R)-2-METHYLOXIRANE-2-YL)-PENTAN-1-ONE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | AMGEN INC. (US) | 2018-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220395820-A1 | ORGANOMETALLIC COMPLEXES OF SEQUENTIAL TETRADENTATE MONOANIONIC LIGANDS AND USES THEREOF IN RING OPENING POLYMERIZATION OF CYCLIC ESTERS | NCLN, NCL, LGMN | L3MBTL1 1533/4885NOS2 509/4885NOS3 578/4885 |
| US-11904307-B2 | Organometallic complexes of sequential tetradentate monoanionic ligands and uses thereof in ring opening polymerization of cyclic esters | NCLN, NCL, LGMN | L3MBTL1 1533/4885NOS2 509/4885NOS3 578/4885 |
| US-11452998-B2 | Organometallic complexes of sequential tetradentate monoanionic ligands and uses thereof in ring opening polymerization of cyclic esters | NCLN, NCL, LGMN | L3MBTL1 1533/4885NOS2 509/4885NOS3 578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.