Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5547642 | 0.87 | BLM (0.31) | — | |
| SCHEMBL5552129 | 0.82 | CA2 (0.37) | CA2 | |
| SCHEMBL3034995 | 0.79 | TDP1 (0.41) | CES2CA1CA2EPHX1CES1 | |
| SCHEMBL19846863 | 0.78 | TSHR (0.44) | TSHRCYP3A4CA1CA2ALDH1A1 | |
| SCHEMBL5586239 | 0.76 | EPHX1 (0.46) | CES2EPHX1CES1FAAH | |
| SCHEMBL19099806 | 0.76 | EPHX1 (0.46) | CES2EPHX1CES1FAAH | |
| SCHEMBL2203447 | 0.76 | EPHX1 (0.46) | CES2EPHX1CES1FAAH | |
| SCHEMBL12902479 | 0.75 | CA1 (0.46) | CA1CA2EPHX1KMT2A | |
| SCHEMBL2202996 | 0.74 | RORC (0.33) | — | |
| SCHEMBL11340320 | 0.73 | CES2 (0.47) | CES2MEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10303079-B2 | Electrophotographic member, process cartridge and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2019-05-28 | — | — | US | disclosed |
| US-20180039200-A1 | ELECTROPHOTOGRAPHIC MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2018-02-08 | — | — | US | disclosed |