Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 16/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 15/20 | 0.41 |
| ▸ | ITK | Q08881 | 2/20 | 0.39 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8269417 | 0.83 | ITK (0.50) | ITKMAP2K4 | |
| SCHEMBL130781 | 0.74 | ITK (0.47) | ITKMAP2K4 | |
| SCHEMBL15078644 | 0.73 | ITK (0.44) | HSP90AA1HSP90AB1ITKMAP2K4LMNA | |
| SCHEMBL12491409 | 0.72 | PRKAB2 (0.46) | HSP90AB1MAP2K4 | |
| SCHEMBL4217250 | 0.71 | HSP90AA1 (0.55) | HSP90AA1HSP90AB1CDK8 | |
| SCHEMBL19272818 | 0.71 | KDM4E (0.36) | HSP90AA1HSP90AB1ITKMAP2K4 | |
| SCHEMBL7216744 | 0.70 | MAP2K4 (0.53) | ITKMAP2K4 | |
| SCHEMBL14564411 | 0.68 | MAPT (0.49) | ITKMAP2K4LMNA | |
| SCHEMBL10189221 | 0.67 | KIF11 (0.47) | MAP2K4LMNA | |
| SCHEMBL22275998 | 0.67 | FFAR1 (0.39) | HSP90AA1HSP90AB1ITKMAP2K4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10179124-B2 | Benzamides and related inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2019-01-15 | — | — | US | disclosed |
| US-20180036296-A1 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA | COR THERAPEUTICS, INC. | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180036296-A1 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA | TFPI, F12, TFPI2 | HSP90AA1 3853/4885HSP90AB1 3531/4885ITK 3933/4885 |
| US-10179124-B2 | Benzamides and related inhibitors of factor Xa | TFPI, F12, TFPI2 | HSP90AA1 3853/4885HSP90AB1 3531/4885ITK 3933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.