Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.33 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24394493 | 0.89 | PNMT (0.49) | TAAR1ALDH1A1HTR2AKCNH2SLC6A4 | |
| SCHEMBL18553014 | 0.85 | TAAR1 (0.38) | TAAR1ALDH1A1NPSR1HTR2AKCNH2 | |
| SCHEMBL27113154 | 0.85 | TAAR1 (0.42) | TAAR1HTR2ASLC6A4HTR2CDAO | |
| SCHEMBL12400878 | 0.85 | TAAR1 (0.38) | TAAR1ALDH1A1NPSR1HTR2AKCNH2 | |
| SCHEMBL18890829 | 0.82 | TAAR1 (0.45) | TAAR1HTR2AKCNH2HTR2CDAO | |
| SCHEMBL19335895 | 0.81 | TAAR1 (0.48) | TAAR1HTR2AKCNH2HTR2CDAO | |
| SCHEMBL18901756 | 0.81 | TAAR1 (0.39) | TAAR1HTR2ASLC6A4HTR2CDAO | |
| SCHEMBL19807365 | 0.81 | ALDH1A1 (0.38) | TAAR1ALDH1A1NPSR1SLC6A4PNMT | |
| SCHEMBL18553016 | 0.79 | TAAR1 (0.45) | TAAR1ALDH1A1NPSR1KCNH2PNMT | |
| SCHEMBL18590775 | 0.79 | TAAR1 (0.45) | TAAR1HTR2AP2RX7DAOFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10179124-B2 | Benzamides and related inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2019-01-15 | — | — | US | disclosed |
| US-20180036296-A1 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA | COR THERAPEUTICS, INC. | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180036296-A1 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA | TFPI, F12, TFPI2 | TAAR1 4680/4885ALDH1A1 2339/4885NPSR1 2795/4885 |
| US-10179124-B2 | Benzamides and related inhibitors of factor Xa | TFPI, F12, TFPI2 | TAAR1 4680/4885ALDH1A1 2339/4885NPSR1 2795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.