Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23240081 | 0.92 | TAAR1 (0.41) | TAAR1PTGS1PTGS2DAOSLC6A2 | |
| SCHEMBL18890829 | 0.86 | TAAR1 (0.45) | TAAR1PTGS1PTGS2DAOHTR2A | |
| SCHEMBL19335895 | 0.85 | TAAR1 (0.48) | TAAR1PTGS1PTGS2DAOHTR2A | |
| SCHEMBL19853526 | 0.85 | TAAR1 (0.39) | TAAR1DAOSLC6A4HTR2AHTR2C | |
| SCHEMBL18901756 | 0.85 | TAAR1 (0.39) | TAAR1PTGS1PTGS2DAOSLC6A2 | |
| SCHEMBL18590775 | 0.83 | TAAR1 (0.45) | TAAR1DAOHTR2ACYP1A2CYP2A6 | |
| SCHEMBL19200848 | 0.83 | HTR2A (0.37) | TAAR1PTGS1PTGS2DAOHTR2A | |
| SCHEMBL20251420 | 0.83 | DAO (0.47) | TAAR1PTGS1PTGS2DAOHTR2A | |
| SCHEMBL20850067 | 0.81 | HTR2A (0.36) | TAAR1DAOHTR2AHTR2CNR3C2 | |
| SCHEMBL18503376 | 0.81 | TAAR1 (0.44) | TAAR1PTGS1PTGS2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | TRPA1, TRPC1, CRY1 | TAAR1 101/4885PTGS1 4117/4885PTGS2 4365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.