SCHEMBL19854543

SCHEMBL19854543

C=CCCCCCCc1ccc(NC(=O)C=C)cc1

nearest known ligand 0.74

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRA P10827 6/20 0.74
THRB P10828 6/20 0.74
TGM2 P21980 12/20 0.50
F13A1 P00488 3/20 0.50
TGM1 P22735 3/20 0.50
LMNA P02545 1/20 0.50
TGM3 Q08188 1/20 0.50
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
SPHK1 Q9NYA1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2728759 0.85 THRB (1.00) THRATHRBMEN1KMT2ASPHK1
SCHEMBL2727638 0.85 THRB (1.00) THRATHRBMEN1KMT2ASPHK1
SCHEMBL9864844 0.85 THRB (1.00) THRATHRBMEN1KMT2ASPHK1
SCHEMBL2729131 0.85 THRB (1.00) THRATHRBMEN1KMT2ASPHK1
SCHEMBL19854529 0.85 THRB (1.00) THRATHRBMEN1KMT2ASPHK1
SCHEMBL29175026 0.83 THRB (0.97) THRATHRBTGM2MEN1KMT2A
SCHEMBL19856025 0.83 THRA (0.58) THRATHRBTGM2F13A1TGM1
SCHEMBL6677167 0.81 THRA (0.88) THRATHRBTGM2F13A1TGM1
SCHEMBL19854526 0.81 THRA (0.53) THRATHRBMEN1KMT2ASPHK1
SCHEMBL2729793 0.80 THRA (0.67) THRATHRBTGM2F13A1TGM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 WO disclosed