Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19853793 | 0.88 | LMNA (0.33) | — | |
| SCHEMBL19854888 | 0.88 | — | — | |
| SCHEMBL19854305 | 0.84 | MME (0.33) | MME | |
| SCHEMBL23153058 | 0.82 | OPRK1 (0.33) | MME | |
| SCHEMBL19853719 | 0.82 | OPRK1 (0.33) | MME | |
| SCHEMBL19853736 | 0.81 | ALOX15 (0.34) | — | |
| SCHEMBL19853729 | 0.81 | — | — | |
| SCHEMBL19854882 | 0.79 | LMNA (0.34) | — | |
| SCHEMBL19854373 | 0.79 | LMNA (0.34) | — | |
| SCHEMBL19853676 | 0.78 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018026763-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | APTINYX INC. (US) | 2018-02-08 | — | — | WO | disclosed |