Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | F7 | P08709 | 2/20 | 0.40 |
| ▸ | F3 | P13726 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 2/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6117357 | 0.80 | LOXL2 (0.51) | HRH4HRH3LOXL2KMT2ASMN1; SMN2 | |
| SCHEMBL5731862 | 0.79 | HRH4 (0.51) | HRH4HRH3LOXL2KMT2ASMN1; SMN2 | |
| SCHEMBL8761869 | 0.78 | HRH4 (0.51) | HRH4HRH3LOXL2KMT2ASMN1; SMN2 | |
| SCHEMBL5103790 | 0.76 | LOXL2 (0.50) | HRH4HRH3LOXL2KMT2ASMN1; SMN2 | |
| SCHEMBL1253869 | 0.75 | LOXL2 (0.58) | HRH4HRH3LOXL2KMT2ASMN1; SMN2 | |
| SCHEMBL1253868 | 0.73 | HRH4 (0.47) | HRH4HRH3LOXL2KMT2ASMN1; SMN2 | |
| SCHEMBL23875945 | 0.70 | HRH4 (0.54) | HRH4HRH3LOXL2KMT2ASMN1; SMN2 | |
| SCHEMBL28390130 | 0.70 | MEN1 (0.54) | HRH4HRH3LOXL2KMT2ASMN1; SMN2 | |
| SCHEMBL2056276 | 0.68 | LOXL2 (0.68) | HRH4HRH3LOXL2KMT2ASMN1; SMN2 | |
| SCHEMBL6117237 | 0.68 | LOXL2 (0.62) | HRH4LOXL2KMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140018377-A1 | Aminopropenoates as Fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-16 | — | — | US | disclosed |
| US-8476197-B2 | Aminopropenoates as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-07-02 | — | — | US | disclosed |
| US-20110152322-A1 | Aminopropenoates as Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152322-A1 | Aminopropenoates as Fungicides | AASDHPPT, DAO, AAAS | HRH4 2296/4885HRH3 2007/4885LOXL2 2927/4885 |
| US-20140018377-A1 | Aminopropenoates as Fungicides | ACMSD, AASDHPPT, AAAS | HRH4 2313/4885HRH3 2411/4885LOXL2 2015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.