Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | MMP14 | P50281 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | PGR | P06401 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | RNF4 | P78317 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PNLIP | P16233 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11411239 | 0.94 | MMP2 (0.51) | MMP2MMP8MMP14CA9CA14 | |
| SCHEMBL19864884 | 0.86 | MMP2 (0.57) | MMP2MMP8MMP14CA9CA14 | |
| SCHEMBL5955152 | 0.82 | MMP2 (0.57) | MMP2MMP8MMP14CA9CA14 | |
| SCHEMBL5955145 | 0.82 | MMP2 (0.57) | MMP2MMP8MMP14CA9CA14 | |
| SCHEMBL5511994 | 0.82 | CA12 (0.50) | CA9HPGDSMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL5954420 | 0.81 | MMP2 (0.55) | MMP2MMP8MMP14CA9CA14 | |
| SCHEMBL5954418 | 0.81 | MMP2 (0.55) | MMP2MMP8MMP14CA9CA14 | |
| SCHEMBL30450762 | 0.80 | HPGD (0.64) | MMP2MMP8MMP14CA9CA14 | |
| SCHEMBL4206636 | 0.79 | RAB9A (0.55) | HPGDSMN1; SMN2TGM2ALDH1A1NPC1 | |
| SCHEMBL5955336 | 0.77 | PPARG (0.63) | MMP2MMP8MMP14CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10239879-B2 | Process for producing purinone derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2019-03-26 | — | — | US | claimed |
| EP-3281943-B1 | PROCESS FOR PRODUCING PURINONE DERIVATIVE | ONO PHARMACEUTICAL CO (JP) | 2023-06-28 | — | — | EP | disclosed |
| US-10239879-B2 | Process for producing purinone derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2019-03-26 | — | — | US | disclosed |
| US-20180079751-A1 | PROCESS FOR PRODUCING PURINONE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2018-03-22 | — | — | US | disclosed |
| EP-3281943-A1 | PROCESS FOR PRODUCING PURINONE DERIVATIVE | ONO Pharmaceutical Co., Ltd. (JP) | 2018-02-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10239879-B2 | Process for producing purinone derivative | PURB, UMPS, UPP1 | MMP2 4026/4885MMP8 3687/4885MMP14 4334/4885 |
| US-20180079751-A1 | PROCESS FOR PRODUCING PURINONE DERIVATIVE | PURB, UMPS, UPP1 | MMP2 4026/4885MMP8 3687/4885MMP14 4334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.