Acetic Acid

Acetic Acid

SCHEMBL19856511

CC(=O)O.CN(C)CCCCCCN(C)C

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.65
TSHR P16473 1/20 0.65
DNM1 Q05193 3/20 0.52
KDM4A O75164 12/20 0.52
KDM4C Q9H3R0 12/20 0.52
KDM5A P29375 1/20 0.52
KDM7A Q6ZMT4 1/20 0.52
PHF8 Q9UPP1 1/20 0.52
KDM2A Q9Y2K7 1/20 0.52
PAOX Q6QHF9 1/20 0.48
SIGMAR1 Q99720 1/20 0.43
FFAR3 O14843 1/20 0.41
LCK P06239 1/20 0.41
FYN P06241 1/20 0.41
KDM4E B2RXH2 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL30060683 0.90 DNM1 (0.71) ALDH1A1TSHRDNM1
Acetic Acid SCHEMBL31440217 0.90 DNM1 (0.71) ALDH1A1TSHRDNM1
Acetic Acid SCHEMBL5568676 0.90 DNM1 (0.71) ALDH1A1TSHRDNM1
Acetic Acid SCHEMBL3915385 0.90 DNM1 (0.71) ALDH1A1TSHRDNM1
Dymanthine SCHEMBL1234152 0.90 DNM1 (0.71) ALDH1A1TSHRDNM1
Acetic Acid SCHEMBL11028728 0.90 DNM1 (0.71) ALDH1A1TSHRDNM1
Acetic Acid SCHEMBL339432 0.90 DNM1 (0.71) ALDH1A1TSHRDNM1
Acetic Acid SCHEMBL10938689 0.90 DNM1 (0.71) ALDH1A1TSHRDNM1
Acetic Acid SCHEMBL829333 0.90 DNM1 (0.71) ALDH1A1TSHRDNM1
Acetic Acid SCHEMBL1427590 0.90 DNM1 (0.71) ALDH1A1TSHRDNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117822321-A Super-hydrophilic softening agent for cotton and preparation method thereof 浙江理工大学桐乡研究院有限公司 2024-04-05 CN claimed
CN-108951172-B Organosilicon softener used in one bath with fluorine-based waterproofing agent and preparation method thereof 上海应用技术大学 2021-05-11 CN claimed
CN-117822321-A Super-hydrophilic softening agent for cotton and preparation method thereof 浙江理工大学桐乡研究院有限公司 2024-04-05 CN disclosed
CN-108951172-B Organosilicon softener used in one bath with fluorine-based waterproofing agent and preparation method thereof 上海应用技术大学 2021-05-11 CN disclosed
CN-108951172-B Organosilicon softener used in one bath with fluorine-based waterproofing agent and preparation method thereof 上海应用技术大学 2021-05-11 CN disclosed
EP-3281933-B1 (METH)ACRYLATE MANUFACTURING METHOD TOAGOSEI CO LTD (JP) 2020-08-19 EP disclosed
US-10266476-B2 (Meth)acrylate manufacturing method TOAGOSEI CO., LTD. (JP) 2019-04-23 US disclosed
US-20180118658-A1 (METH)ACRYLATE MANUFACTURING METHOD TOAGOSEI CO., LTD. (JP) 2018-05-03 US disclosed
EP-3281933-A1 (METH)ACRYLATE MANUFACTURING METHOD Toagosei Co., Ltd. (JP) 2018-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118658-A1 (METH)ACRYLATE MANUFACTURING METHOD MMAB, PAM, MAT2B ALDH1A1 264/4885TSHR 1174/4885DNM1 952/4885
US-10266476-B2 (Meth)acrylate manufacturing method MMAB, PAM, MAT2B ALDH1A1 264/4885TSHR 1174/4885DNM1 952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.