Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.37 |
| ▸ | CYP51A1 | Q16850 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | UGCG | Q16739 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | STAT6 | P42226 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19856873 | 1.00 | PYGL (0.38) | PYGLDRD2HTRA1CYP51A1ALOX15 | |
| SCHEMBL7942666 | 0.87 | STAT6 (0.42) | PYGLCYP51A1ALOX15DRD3UGCG | |
| SCHEMBL19856883 | 0.86 | ALOX15 (0.42) | PYGLDRD2CYP51A1ALOX15DRD3 | |
| SCHEMBL19856882 | 0.86 | ALOX15 (0.42) | PYGLDRD2CYP51A1ALOX15DRD3 | |
| SCHEMBL19856898 | 0.84 | PYGL (0.43) | PYGLDRD2CYP51A1ALOX15DRD3 | |
| SCHEMBL19856896 | 0.84 | PYGL (0.43) | PYGLDRD2CYP51A1ALOX15DRD3 | |
| SCHEMBL1550411 | 0.84 | ALOX15 (0.48) | PYGLDRD2CYP51A1ALOX15SMYD3 | |
| SCHEMBL1550025 | 0.84 | PYGL (0.48) | PYGLDRD2CYP51A1SMYD3 | |
| SCHEMBL19856879 | 0.83 | DRD2 (0.43) | PYGLDRD2CYP51A1ALOX15DRD3 | |
| SCHEMBL19856881 | 0.83 | DRD2 (0.43) | PYGLDRD2CYP51A1ALOX15DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |