Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 7/20 | 0.47 |
| ▸ | PYGL | P06737 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | CYP51A1 | Q16850 | 4/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19856893 | 1.00 | CCR1 (0.47) | CCR1PYGLDRD2STAT6CYP51A1 | |
| SCHEMBL7942245 | 1.00 | CCR1 (0.47) | CCR1PYGLDRD2STAT6CYP51A1 | |
| SCHEMBL7942248 | 0.87 | DRD2 (0.42) | PYGLDRD2STAT6CYP51A1GAA | |
| SCHEMBL19856884 | 0.87 | DRD2 (0.42) | PYGLDRD2STAT6CYP51A1GAA | |
| SCHEMBL19856886 | 0.87 | DRD2 (0.42) | PYGLDRD2STAT6CYP51A1GAA | |
| SCHEMBL19856885 | 0.87 | DRD2 (0.42) | PYGLDRD2STAT6CYP51A1GAA | |
| SCHEMBL19856900 | 0.87 | DRD2 (0.42) | PYGLDRD2STAT6CYP51A1GAA | |
| SCHEMBL19856968 | 0.87 | CCKBR (0.44) | DRD2STAT6CYP51A1HTRA1 | |
| SCHEMBL19856967 | 0.87 | CCKBR (0.44) | DRD2STAT6CYP51A1HTRA1 | |
| SCHEMBL19856881 | 0.85 | DRD2 (0.43) | CCR1PYGLDRD2STAT6CYP51A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |