Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | HTRA1 | Q92743 | 2/20 | 0.42 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19856968 | 1.00 | CCKBR (0.44) | CCKBRDRD2STAT6FAAHHTRA1 | |
| SCHEMBL19856900 | 0.91 | DRD2 (0.42) | CCKBRDRD2STAT6HTRA1CYP51A1 | |
| SCHEMBL19856884 | 0.91 | DRD2 (0.42) | CCKBRDRD2STAT6HTRA1CYP51A1 | |
| SCHEMBL19856886 | 0.91 | DRD2 (0.42) | CCKBRDRD2STAT6HTRA1CYP51A1 | |
| SCHEMBL19856885 | 0.91 | DRD2 (0.42) | CCKBRDRD2STAT6HTRA1CYP51A1 | |
| SCHEMBL7942248 | 0.91 | DRD2 (0.42) | CCKBRDRD2STAT6HTRA1CYP51A1 | |
| SCHEMBL1931303 | 0.87 | DRD2 (0.47) | DRD2STAT6CYP51A1KDM4ECNR2 | |
| SCHEMBL1931683 | 0.87 | DRD2 (0.47) | DRD2STAT6CYP51A1KDM4ECNR2 | |
| SCHEMBL1931738 | 0.87 | DRD2 (0.47) | DRD2STAT6CYP51A1KDM4ECNR2 | |
| SCHEMBL14964347 | 0.87 | DRD2 (0.47) | CCKBRDRD2STAT6CYP51A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |