Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 2/20 | 0.38 |
| ▸ | CCKBR | P32239 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19856934 | 0.95 | STAT6 (0.43) | STAT6DRD2CYP51A1PYGLCCKBR | |
| SCHEMBL19856906 | 0.84 | DRD2 (0.45) | STAT6DRD2CYP51A1PYGLCCKBR | |
| SCHEMBL19856870 | 0.83 | DRD2 (0.43) | STAT6DRD2CYP51A1PYGLCCKBR | |
| SCHEMBL19856869 | 0.83 | DRD2 (0.43) | STAT6DRD2CYP51A1PYGLCCKBR | |
| SCHEMBL14964347 | 0.83 | DRD2 (0.47) | STAT6DRD2CYP51A1PYGLCCKBR | |
| SCHEMBL1549906 | 0.82 | DRD2 (0.42) | STAT6DRD2CYP51A1TAS1R3TAS1R1 | |
| SCHEMBL4051134 | 0.82 | DRD2 (0.38) | STAT6DRD2CYP51A1PYGLCCKBR | |
| SCHEMBL4053233 | 0.81 | STAT6 (0.40) | STAT6DRD2CYP51A1TAS1R3TAS1R1 | |
| SCHEMBL1931738 | 0.81 | DRD2 (0.47) | STAT6DRD2CYP51A1PYGLTAS1R3 | |
| SCHEMBL1931303 | 0.81 | DRD2 (0.47) | STAT6DRD2CYP51A1PYGLTAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925857-B1 | USE OF TRPV4 ANTAGONISTS TO AMELIORATE HYDROCEPHALUS AND RELATED MATERIALS AND METHODS | UNIV INDIANA RES & TECH CORP (US) | 2018-02-14 | — | — | EP | claimed |