Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 11/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27817013 | 0.98 | VCAM1 (0.44) | VCAM1TDP1TSHRMAPK1ALDH1A1 | |
| SCHEMBL231697 | 0.83 | TSHR (0.48) | VCAM1TDP1TSHRMAPK1ALDH1A1 | |
| SCHEMBL57882 | 0.80 | TSHR (0.40) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL3456576 | 0.79 | VCAM1 (0.31) | VCAM1 | |
| SCHEMBL6800906 | 0.78 | TDP1 (0.38) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL2221806 | 0.77 | HPGD (0.41) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL1028967 | 0.77 | TDP1 (0.50) | TDP1TSHRMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL58127 | 0.77 | HSD17B10 (0.54) | TDP1TSHRALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL710076 | 0.75 | ALDH1A1 (0.47) | VCAM1TDP1TSHRMAPK1ALDH1A1 | |
| SCHEMBL1028675 | 0.75 | GPR35 (0.47) | TDP1TSHRMAPK1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2066 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290379-A | Preparation method of novel agricultural multifunctional substance and application of novel agricultural multifunctional substance in aspects of resisting virus, inhibiting bacteria and promoting plant growth | 贵州工业职业技术学院 | 2024-07-05 | — | — | CN | claimed |
| CN-117658933-A | 1,2, 4-triazolol substituted benzenesulfonamide derivatives | 贵阳学院 | 2024-03-08 | — | — | CN | claimed |
| US-20230303561-A1 | PYRIMIDINONE DERIVATIVE, PREPARATION METHOD THEREOF AND USE THEREOF IN RESISTING MYCOBACTERIUM TUBERCULOSIS INFECTION | INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2023-09-28 | — | — | US | claimed |
| CN-114436909-B | Sulfonyl sabinol derivative and preparation method and application thereof | 河南科技大学 | 2023-05-30 | — | — | CN | claimed |
| EP-4180429-A1 | PYRIMIDINONE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF AGAINST MYCOBACTERIUM TUBERCULOSIS INFECTION | Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences (CN) | 2023-05-17 | — | — | EP | claimed |
| CN-114436909-A | Sulfonyl hinokitiol derivative and its prepn and application | 河南科技大学 | 2022-05-06 | — | — | CN | claimed |
| CN-110240533-B | Preparation method of N, N-dimethyl sulfonamide derivative | 河南科技大学 | 2022-03-18 | — | — | CN | claimed |
| CN-114081890-A | Application of pyrimidone derivatives in resisting mycobacterium tuberculosis infection | 中国医学科学院医药生物技术研究所 | 2022-02-25 | — | — | CN | claimed |
| CN-111925368-B | Pyrimidone derivatives, preparation method thereof and application thereof in resisting mycobacterium tuberculosis infection | 中国医学科学院医药生物技术研究所 | 2021-11-05 | — | — | CN | claimed |
| CN-110627692-B | Paeonol benzenesulfonylhydrazone and derivative thereof, preparation method of paeonol benzenesulfonylhydrazone and derivative thereof, botanical insecticide and application of botanical insecticide | 河南科技大学 | 2021-09-24 | — | — | CN | claimed |
| WO-1991010642-A1 | PROCESS FOR PREPARING HOMOCHIRAL AMINES AND PROCESS FOR PREPARING INTERMEDIATES FOR THE PREPARATION THEREOF, AND THE INTERMEDIATES PREPARED IN ACCORDANCE WITH THIS PROCESS | NOBEL CHEMICALS AB (SE) | 1991-07-25 | — | — | WO | claimed |
| US-4876274-A | INSECTICIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1989-10-24 | — | — | US | claimed |
| EP-0128462-B1 | NOVEL BENZOTHIAZEPINE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITIONS | Tanabe Seiyaku Co., Ltd. (JP) | 1989-03-22 | — | — | EP | claimed |
| US-4521430-A | VASODILATOR, ANTIISCHEMIC AGENT | TANABE SEIYAKU CO., LTD. (JP) | 1985-06-04 | — | — | US | claimed |
| EP-0128462-A1 | Novel benzothiazepine derivatives, processes for preparing the same and pharmaceutical compositions | Tanabe Seiyaku Co., Ltd. (JP) | 1984-12-19 | — | — | EP | claimed |
| US-4213898-A | FOR POLYACRYLONITRILE | SANDOZ LTD. (CH) | 1980-07-22 | — | — | US | claimed |
| US-4061751-A | 6-Substituted 3-nitroimidazo[1,2-b]pyridazine for the control of foot rot and liver lesions in ruminant animals | AMERICAN CYANAMID COMPANY (US) | 1977-12-06 | — | — | US | claimed |
| US-4060614-A | 6-Substituted 3-nitroimidazo[1,2-b]pyridazine for the control of hemorrhagic colitis in swine | AMERICAN CYANAMID COMPANY (US) | 1977-11-29 | — | — | US | claimed |
| US-4046757-A | 2-Optionally substituted alkyl-and phenylsulfonylphenyl-azo-phenyl dyes and a process for their synthesis | SANDOZ LTD. (CH) | 1977-09-06 | — | — | US | claimed |
| US-3998803-A | TEXTILES | FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) | 1976-12-21 | — | — | US | claimed |