Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29172280 | 0.83 | PARP1 (0.37) | PARP1TDP1KMT2ATSHRMEN1 | |
| SCHEMBL57882 | 0.80 | TSHR (0.40) | TDP1KMT2ATSHRMEN1CYP3A4 | |
| SCHEMBL6800906 | 0.78 | TDP1 (0.38) | TDP1KMT2ATSHRMEN1CYP3A4 | |
| SCHEMBL1028967 | 0.77 | TDP1 (0.50) | TDP1KMT2ATSHRMEN1CYP3A4 | |
| SCHEMBL58127 | 0.77 | HSD17B10 (0.54) | TDP1TSHRCYP3A4ALDH1A1MAPT | |
| SCHEMBL710076 | 0.75 | ALDH1A1 (0.47) | TDP1KMT2ATSHRMEN1CYP3A4 | |
| SCHEMBL1028675 | 0.75 | GPR35 (0.47) | TDP1KMT2ATSHRMEN1CYP3A4 | |
| SCHEMBL5675005 | 0.75 | TDP1 (0.35) | TDP1KMT2ATSHRMEN1CYP3A4 | |
| SCHEMBL232839 | 0.75 | TDP1 (0.39) | TDP1KMT2ATSHRMEN1CYP3A4 | |
| SCHEMBL19859 | 0.75 | VCAM1 (0.46) | TDP1TSHRCYP3A4ALDH1A1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279698-A2 | Pesticidal compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-08-24 | — | — | EP | claimed |
| EP-2900645-B1 | HERBICIDAL AND FUNGICIDAL 3-PHENYLISOXAZOLIN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2019-08-21 | — | — | EP | disclosed |
| CN-110062757-A | Plasma thromboplastin antecedent a inhibitor and application thereof | 广东东阳光药业有限公司 | 2019-07-26 | — | — | CN | disclosed |
| EP-2576529-B1 | Heterocyclic alkanol derivatives as fungicides | BAYER IP GMBH (DE) | 2017-05-24 | — | — | EP | disclosed |
| US-9585392-B2 | 3-phenylisoxazolin derivatives with herbicidal action | BAYER CROPSCIENCE AG (DE) | 2017-03-07 | — | — | US | disclosed |
| US-20150245615-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | BAYER CROPSCIENCE AG (DE) | 2015-09-03 | — | — | US | disclosed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| CN-103857681-A | Novel macrocycles as factor XIA inhibitors | BRISTOL MYERS SQUIBB CO | 2014-06-11 | — | — | CN | disclosed |
| CN-103702999-A | Cyclic p1 linkers as factor xia inhibitors | BRISTOL MYERS SQUIBB CO | 2014-04-02 | — | — | CN | disclosed |
| US-8436189-B2 | Heterocyclic alkanol derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-05-07 | — | — | US | disclosed |
| EP-2576529-A1 | HETEROCYCLIC ALKANOL DERIVATIVES AS FUNGICIDES | Bayer Intellectual Property GmbH (DE) | 2013-04-10 | — | — | EP | disclosed |
| CN-102947282-A | Heterocyclic alkanol derivatives as fungicides | BAYER CROPSCIENCE AG | 2013-02-27 | — | — | CN | disclosed |
| US-20120004102-A1 | Novel Heterocyclic Alkanol Derivatives | BAYER CROPSCIENCE AG (DE) | 2012-01-05 | — | — | US | disclosed |
| WO-2011147815-A1 | HETEROCYCLIC ALKANOL DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-12-01 | — | — | WO | disclosed |
| EP-0279698-A2 | Pesticidal compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-08-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150245615-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | CYP4X1, CBR3, PAOX | PARP1 2153/4885TDP1 2034/4885KMT2A 2596/4885 |
| US-20120004102-A1 | Novel Heterocyclic Alkanol Derivatives | ERG28, CBR3, MYB | PARP1 966/4885TDP1 2721/4885KMT2A 2689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.